Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2665862..2666133 Replicon chromosome
Accession NZ_CP010443
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2665900..2666003 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2665862..2666133 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH04_RS13210 2663019..2664458 + 1440 Protein_2496 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SH04_RS13215 2664576..2664812 + 237 WP_001295499.1 DUF1480 family protein -
SH04_RS13220 2664917..2665108 + 192 WP_000457842.1 YebW family protein -
SH04_RS13225 2665109..2665765 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2665862..2666133 + 272 - - Antitoxin
- 2665900..2666003 - 104 - - Toxin
SH04_RS13235 2666161..2666502 - 342 WP_000976476.1 YebY family protein -
SH04_RS13240 2666515..2667387 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SH04_RS13245 2667391..2667765 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SH04_RS13250 2667904..2668134 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SH04_RS13255 2668236..2668892 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SH04_RS13260 2668916..2669578 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52632 NZ_CP010443:c2666003-2665900 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52632 NZ_CP010443:2665862-2666133 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References