Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2666636..2666907 Replicon chromosome
Accession NZ_CP010441
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2666674..2666777 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2666636..2666907 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH03_RS13220 2663793..2665232 + 1440 Protein_2497 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SH03_RS13225 2665350..2665586 + 237 WP_001295499.1 DUF1480 family protein -
SH03_RS13230 2665691..2665882 + 192 WP_000457842.1 YebW family protein -
SH03_RS13235 2665883..2666539 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2666636..2666907 + 272 - - Antitoxin
- 2666674..2666777 - 104 - - Toxin
SH03_RS13245 2666935..2667276 - 342 WP_000976476.1 YebY family protein -
SH03_RS13250 2667289..2668161 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SH03_RS13255 2668165..2668539 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SH03_RS13260 2668678..2668908 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SH03_RS13265 2669010..2669666 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SH03_RS13270 2669690..2670352 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52549 NZ_CP010441:c2666777-2666674 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52549 NZ_CP010441:2666636-2666907 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References