Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2680174..2680445 Replicon chromosome
Accession NZ_CP010440
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2680212..2680315 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2680174..2680445 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH08_RS13315 2677331..2678770 + 1440 Protein_2522 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SH08_RS13320 2678888..2679124 + 237 WP_001295499.1 DUF1480 family protein -
SH08_RS13325 2679229..2679420 + 192 WP_000457842.1 YebW family protein -
SH08_RS13330 2679421..2680077 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2680174..2680445 + 272 - - Antitoxin
- 2680212..2680315 - 104 - - Toxin
SH08_RS13340 2680473..2680814 - 342 WP_000976476.1 YebY family protein -
SH08_RS13345 2680827..2681699 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SH08_RS13350 2681703..2682077 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SH08_RS13355 2682216..2682446 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SH08_RS13360 2682548..2683204 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SH08_RS13365 2683228..2683890 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52508 NZ_CP010440:c2680315-2680212 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52508 NZ_CP010440:2680174-2680445 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References