Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2678731..2679002 Replicon chromosome
Accession NZ_CP010438
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2678769..2678872 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2678731..2679002 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SH05_RS13320 2675888..2677327 + 1440 Protein_2521 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SH05_RS13325 2677445..2677681 + 237 WP_001295499.1 DUF1480 family protein -
SH05_RS13330 2677786..2677977 + 192 WP_000457842.1 YebW family protein -
SH05_RS13335 2677978..2678634 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2678731..2679002 + 272 - - Antitoxin
- 2678769..2678872 - 104 - - Toxin
SH05_RS13345 2679030..2679371 - 342 WP_000976476.1 YebY family protein -
SH05_RS13350 2679384..2680256 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SH05_RS13355 2680260..2680634 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SH05_RS13360 2680773..2681003 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SH05_RS13365 2681105..2681761 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SH05_RS13370 2681785..2682447 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52437 NZ_CP010438:c2678872-2678769 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52437 NZ_CP010438:2678731-2679002 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References