Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 426641..427149 Replicon chromosome
Accession NZ_CP010427
Organism Allofrancisella guangzhouensis strain 08HL01032

Toxin (Protein)


Gene name relB Uniprot ID A0A0A8E3H3
Locus tag SD28_RS01940 Protein ID WP_039123469.1
Coordinates 426641..426895 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A0A8E2S9
Locus tag SD28_RS01945 Protein ID WP_039123470.1
Coordinates 426892..427149 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SD28_RS01910 423112..423711 + 600 WP_039123464.1 hypothetical protein -
SD28_RS08050 423696..423854 + 159 WP_157698616.1 hypothetical protein -
SD28_RS01915 423823..424200 + 378 WP_157698617.1 hypothetical protein -
SD28_RS01920 424212..424565 + 354 WP_039123465.1 hypothetical protein -
SD28_RS01925 424603..424800 + 198 WP_052251856.1 hypothetical protein -
SD28_RS01930 424811..425404 + 594 WP_157698618.1 hypothetical protein -
SD28_RS01935 425525..426220 + 696 WP_039123468.1 hypothetical protein -
SD28_RS01940 426641..426895 - 255 WP_039123469.1 Txe/YoeB family addiction module toxin Toxin
SD28_RS01945 426892..427149 - 258 WP_039123470.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SD28_RS01950 427779..429017 + 1239 WP_039123471.1 group II intron reverse transcriptase/maturase -
SD28_RS01955 429618..430856 + 1239 WP_039123471.1 group II intron reverse transcriptase/maturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10475.90 Da        Isoelectric Point: 9.5944

>T52397 WP_039123469.1 NZ_CP010427:c426895-426641 [Allofrancisella guangzhouensis]
MILSWSTNAWEDYLYWQANDKKKLKRINQLIKDISRNYFEGLGDPEPLKHNWTNYWSRRIDREHRLIYKIQDNSILIAQC
RYHY

Download         Length: 255 bp

>T52397 NZ_CP010427:c426895-426641 [Allofrancisella guangzhouensis]
ATGATATTATCCTGGTCTACTAATGCCTGGGAAGATTATCTTTACTGGCAAGCTAATGATAAAAAAAAGCTTAAGCGTAT
AAATCAGTTAATAAAAGATATCTCAAGAAACTATTTTGAAGGTTTGGGTGATCCAGAACCACTTAAACATAATTGGACTA
ATTATTGGTCTAGAAGGATAGATAGAGAACATAGATTAATTTATAAAATTCAAGATAATAGTATTTTGATTGCTCAATGT
AGATATCACTACTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9727.88 Da        Isoelectric Point: 4.6388

>AT52397 WP_039123470.1 NZ_CP010427:c427149-426892 [Allofrancisella guangzhouensis]
MKTLNYTSFRSELASSMDRVVEDHQPIVVTRGSDKKAVVVMSLDDFKSYQETAHLMSSINNYNRLNDSIEELESGKSIQK
ELIEE

Download         Length: 258 bp

>AT52397 NZ_CP010427:c427149-426892 [Allofrancisella guangzhouensis]
ATGAAAACTTTAAACTATACATCTTTCAGAAGCGAACTAGCATCCTCAATGGATAGAGTTGTAGAAGATCACCAACCTAT
TGTTGTTACAAGGGGTTCTGATAAAAAAGCAGTTGTTGTGATGTCTTTAGATGATTTTAAATCGTACCAAGAAACAGCCC
ATTTAATGTCTAGTATAAATAATTATAATAGACTTAACGACTCTATAGAAGAGCTTGAGTCTGGTAAATCAATACAAAAA
GAGCTTATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A8E3H3

Antitoxin

Source ID Structure
AlphaFold DB A0A0A8E2S9

References