Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 208431..209314 | Replicon | plasmid pAcX50f |
| Accession | NZ_CP010421 | ||
| Organism | Azotobacter chroococcum NCIMB 8003 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | Achr_RS22920 | Protein ID | WP_040107416.1 |
| Coordinates | 208877..209314 (+) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | PrcA | Uniprot ID | A0A0C4WTA4 |
| Locus tag | Achr_RS22915 | Protein ID | WP_040107266.1 |
| Coordinates | 208431..208880 (+) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Achr_RS22895 | 206320..206763 | + | 444 | WP_040107412.1 | hypothetical protein | - |
| Achr_RS22900 | 206939..207190 | + | 252 | WP_040107413.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| Achr_RS22905 | 207190..207606 | + | 417 | WP_040107414.1 | type II toxin-antitoxin system VapC family toxin | - |
| Achr_RS22910 | 207784..208173 | - | 390 | WP_082045705.1 | hypothetical protein | - |
| Achr_RS22915 | 208431..208880 | + | 450 | WP_040107266.1 | DUF2384 domain-containing protein | Antitoxin |
| Achr_RS22920 | 208877..209314 | + | 438 | WP_040107416.1 | RES family NAD+ phosphorylase | Toxin |
| Achr_RS22925 | 209325..209720 | + | 396 | WP_040107417.1 | hypothetical protein | - |
| Achr_RS24770 | 209825..210118 | + | 294 | WP_082045675.1 | hypothetical protein | - |
| Achr_RS22930 | 210241..210513 | - | 273 | WP_040107418.1 | HU family DNA-binding protein | - |
| Achr_RS22935 | 210567..210806 | - | 240 | WP_040107517.1 | hypothetical protein | - |
| Achr_RS22940 | 211402..211974 | - | 573 | WP_158319698.1 | hypothetical protein | - |
| Achr_RS25665 | 212013..212633 | - | 621 | WP_144411481.1 | IS630 family transposase | - |
| Achr_RS25670 | 212623..212964 | - | 342 | WP_158319635.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..311724 | 311724 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15929.24 Da Isoelectric Point: 5.1577
>T52391 WP_040107416.1 NZ_CP010421:208877-209314 [Azotobacter chroococcum NCIMB 8003]
VILWRISAYADLSGIGGLRASGRWHHLGRPVVYAADSPAGAMLEVLVHLEIDPEDFPTTLQLIRIELSDPVSRAELPPLP
EHWKSDPEVTRAMGDRFLDGRSALLLPVPSAIIPCTTNYLFNPAHPEANGASIQAEKFPFDSRLL
VILWRISAYADLSGIGGLRASGRWHHLGRPVVYAADSPAGAMLEVLVHLEIDPEDFPTTLQLIRIELSDPVSRAELPPLP
EHWKSDPEVTRAMGDRFLDGRSALLLPVPSAIIPCTTNYLFNPAHPEANGASIQAEKFPFDSRLL
Download Length: 438 bp
>T52391 NZ_CP010421:208877-209314 [Azotobacter chroococcum NCIMB 8003]
GTGATTTTGTGGCGGATCAGTGCCTACGCCGACCTCAGCGGAATCGGCGGCCTGCGCGCCAGTGGCCGGTGGCACCACCT
TGGCAGGCCGGTCGTTTACGCGGCGGACAGCCCGGCCGGGGCGATGCTGGAGGTGCTTGTCCACCTGGAAATCGACCCGG
AGGACTTCCCCACGACGCTCCAGTTGATCCGCATCGAGCTTTCGGACCCGGTTTCGCGGGCCGAGCTTCCGCCCCTACCG
GAGCACTGGAAGTCGGACCCGGAAGTCACGCGCGCCATGGGTGATCGCTTCCTGGATGGGCGAAGCGCTCTGCTGCTCCC
GGTGCCGAGCGCCATCATTCCCTGCACGACCAACTACCTATTCAATCCGGCGCACCCCGAGGCCAATGGGGCGAGCATCC
AGGCAGAGAAATTCCCCTTCGATTCCCGTCTCCTCTGA
GTGATTTTGTGGCGGATCAGTGCCTACGCCGACCTCAGCGGAATCGGCGGCCTGCGCGCCAGTGGCCGGTGGCACCACCT
TGGCAGGCCGGTCGTTTACGCGGCGGACAGCCCGGCCGGGGCGATGCTGGAGGTGCTTGTCCACCTGGAAATCGACCCGG
AGGACTTCCCCACGACGCTCCAGTTGATCCGCATCGAGCTTTCGGACCCGGTTTCGCGGGCCGAGCTTCCGCCCCTACCG
GAGCACTGGAAGTCGGACCCGGAAGTCACGCGCGCCATGGGTGATCGCTTCCTGGATGGGCGAAGCGCTCTGCTGCTCCC
GGTGCCGAGCGCCATCATTCCCTGCACGACCAACTACCTATTCAATCCGGCGCACCCCGAGGCCAATGGGGCGAGCATCC
AGGCAGAGAAATTCCCCTTCGATTCCCGTCTCCTCTGA
Antitoxin
Download Length: 150 a.a. Molecular weight: 16978.55 Da Isoelectric Point: 6.7345
>AT52391 WP_040107266.1 NZ_CP010421:208431-208880 [Azotobacter chroococcum NCIMB 8003]
MLAEVLRDHGYTAYRARLQSLLDIPESATDFEIHTRITKGFPATRLVQLTEAGVVTPLERDQIIPLRTLKSRIERDQPLT
VEESDRFFRAAHITAMAEAVFGDREKARRWLSKPKERFAGLTPMQMLTTQQGTSQVEEMLLQIVEGLAL
MLAEVLRDHGYTAYRARLQSLLDIPESATDFEIHTRITKGFPATRLVQLTEAGVVTPLERDQIIPLRTLKSRIERDQPLT
VEESDRFFRAAHITAMAEAVFGDREKARRWLSKPKERFAGLTPMQMLTTQQGTSQVEEMLLQIVEGLAL
Download Length: 450 bp
>AT52391 NZ_CP010421:208431-208880 [Azotobacter chroococcum NCIMB 8003]
ATGCTTGCTGAAGTCCTGCGTGACCATGGCTACACCGCATACCGGGCGCGCCTTCAAAGCCTGCTGGACATCCCGGAGTC
GGCAACCGACTTCGAGATCCACACCCGGATCACCAAGGGCTTTCCTGCAACCCGCCTGGTGCAGCTGACCGAGGCGGGAG
TGGTTACGCCGCTGGAGCGCGACCAGATCATTCCCCTGCGCACCCTCAAGAGCCGCATCGAGCGCGATCAGCCGTTGACC
GTGGAGGAAAGCGACAGGTTCTTTCGCGCCGCCCACATCACGGCGATGGCCGAAGCCGTCTTCGGCGACCGCGAGAAGGC
CAGGCGCTGGCTCTCCAAACCCAAGGAGCGGTTTGCCGGCCTGACGCCCATGCAGATGCTGACCACCCAGCAGGGCACCA
GCCAGGTGGAGGAAATGCTGCTGCAGATCGTTGAGGGCCTGGCCCTGTGA
ATGCTTGCTGAAGTCCTGCGTGACCATGGCTACACCGCATACCGGGCGCGCCTTCAAAGCCTGCTGGACATCCCGGAGTC
GGCAACCGACTTCGAGATCCACACCCGGATCACCAAGGGCTTTCCTGCAACCCGCCTGGTGCAGCTGACCGAGGCGGGAG
TGGTTACGCCGCTGGAGCGCGACCAGATCATTCCCCTGCGCACCCTCAAGAGCCGCATCGAGCGCGATCAGCCGTTGACC
GTGGAGGAAAGCGACAGGTTCTTTCGCGCCGCCCACATCACGGCGATGGCCGAAGCCGTCTTCGGCGACCGCGAGAAGGC
CAGGCGCTGGCTCTCCAAACCCAAGGAGCGGTTTGCCGGCCTGACGCCCATGCAGATGCTGACCACCCAGCAGGGCACCA
GCCAGGTGGAGGAAATGCTGCTGCAGATCGTTGAGGGCCTGGCCCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|