Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2699728..2700070 Replicon chromosome
Accession NZ_CP010409
Organism Xanthomonas sacchari strain R1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6N7QE65
Locus tag SB85_RS11340 Protein ID WP_026143575.1
Coordinates 2699728..2699862 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A6N7QPX8
Locus tag SB85_RS11345 Protein ID WP_017908941.1
Coordinates 2699918..2700070 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SB85_RS11315 2695286..2695453 - 168 WP_082028909.1 peptidase -
SB85_RS11320 2695562..2696494 - 933 WP_043093608.1 MBL fold metallo-hydrolase -
SB85_RS11325 2696910..2698202 - 1293 WP_043093610.1 tryptophan--tRNA ligase -
SB85_RS11330 2698368..2699255 + 888 WP_043093611.1 hypothetical protein -
SB85_RS11335 2699326..2699541 - 216 WP_043093613.1 CsbD family protein -
SB85_RS11340 2699728..2699862 - 135 WP_026143575.1 entericidin A/B family lipoprotein Toxin
SB85_RS11345 2699918..2700070 - 153 WP_017908941.1 entericidin A/B family lipoprotein Antitoxin
SB85_RS11350 2700213..2701136 - 924 WP_043095323.1 arginase -
SB85_RS11355 2701291..2701632 + 342 WP_082028798.1 hypothetical protein -
SB85_RS22085 2702044..2702892 - 849 WP_043093616.1 hypothetical protein -
SB85_RS11370 2702990..2703733 - 744 WP_043093618.1 type III pantothenate kinase -
SB85_RS11375 2703730..2704695 - 966 WP_043095325.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4628.46 Da        Isoelectric Point: 10.2066

>T52364 WP_026143575.1 NZ_CP010409:c2699862-2699728 [Xanthomonas sacchari]
MKRTFAWMLLAMFSVGLLAGCNTVAGAGKDVQKAGEKVQDAAKN

Download         Length: 135 bp

>T52364 NZ_CP010409:c2699862-2699728 [Xanthomonas sacchari]
ATGAAGCGTACGTTTGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGGCCGGTTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCAGGCGAGAAGGTCCAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5181.14 Da        Isoelectric Point: 8.1219

>AT52364 WP_017908941.1 NZ_CP010409:c2700070-2699918 [Xanthomonas sacchari]
MKRLTTLLMLTLFCAGVLTGCNTVAGAGKDMQKAGEKVEDTAKDCSAGKC

Download         Length: 153 bp

>AT52364 NZ_CP010409:c2700070-2699918 [Xanthomonas sacchari]
ATGAAGCGACTGACCACCCTGTTGATGCTGACCCTGTTTTGCGCTGGTGTGCTGACCGGCTGCAACACCGTTGCCGGCGC
CGGCAAGGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACACCGCCAAGGATTGCAGCGCGGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6N7QE65

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7QPX8

References