Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1831219..1831724 Replicon chromosome
Accession NZ_CP010409
Organism Xanthomonas sacchari strain R1

Toxin (Protein)


Gene name relE Uniprot ID A0A0A8E0L7
Locus tag SB85_RS07475 Protein ID WP_017907918.1
Coordinates 1831467..1831724 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6N7Q778
Locus tag SB85_RS07470 Protein ID WP_017907919.1
Coordinates 1831219..1831470 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SB85_RS07460 1826599..1829691 + 3093 WP_208602439.1 error-prone DNA polymerase -
SB85_RS20845 1829818..1830102 - 285 WP_082028761.1 DUF3892 domain-containing protein -
SB85_RS07465 1830307..1831056 - 750 WP_043092920.1 endonuclease -
SB85_RS07470 1831219..1831470 + 252 WP_017907919.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SB85_RS07475 1831467..1831724 + 258 WP_017907918.1 Txe/YoeB family addiction module toxin Toxin
SB85_RS07485 1831989..1832342 - 354 WP_010342469.1 PilZ domain-containing protein -
SB85_RS07490 1832339..1833301 - 963 WP_043092921.1 DNA polymerase III subunit delta' -
SB85_RS07495 1833298..1833969 - 672 WP_043092923.1 dTMP kinase -
SB85_RS07500 1833966..1835027 - 1062 WP_043095212.1 endolytic transglycosylase MltG -
SB85_RS07505 1835102..1836451 - 1350 WP_043092926.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1821945..1832342 10397


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10223.75 Da        Isoelectric Point: 9.6589

>T52363 WP_017907918.1 NZ_CP010409:1831467-1831724 [Xanthomonas sacchari]
VTLQFSDNAWEDYLYWQQADKKMLKRINDLIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKVEHGVLLIAQV
RYHYV

Download         Length: 258 bp

>T52363 NZ_CP010409:1831467-1831724 [Xanthomonas sacchari]
GTGACGCTGCAGTTCTCGGACAACGCCTGGGAGGATTATCTCTACTGGCAACAGGCCGACAAAAAGATGCTCAAGCGCAT
CAACGACCTGATCAAGGCCATTCAACGCGATCCCTTCCAGGGCATCGGCAAACCCGAACCGCTACGCCATGCACTTGCAG
GCTACTGGTCGCGACGCATCAACGACGAACACCGGATCGTCTACAAGGTCGAGCATGGCGTTCTGCTGATTGCACAAGTG
CGATATCACTACGTTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9324.59 Da        Isoelectric Point: 5.1186

>AT52363 WP_017907919.1 NZ_CP010409:1831219-1831470 [Xanthomonas sacchari]
MDTITYSAARAALADTMDRVVNNHEPVIITRSREQAVVMLSLEDYKAMEETAYLLRSPKNAQRLLESIAQLESGRGKARE
LSE

Download         Length: 252 bp

>AT52363 NZ_CP010409:1831219-1831470 [Xanthomonas sacchari]
ATGGACACCATCACCTACAGCGCCGCACGTGCCGCTCTCGCGGACACCATGGACCGCGTGGTCAACAACCACGAGCCGGT
GATCATCACACGCAGCCGCGAGCAAGCCGTTGTCATGCTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACTGCCTATC
TGCTGCGCAGCCCGAAGAACGCGCAGCGCTTGCTGGAATCCATCGCCCAACTCGAATCCGGTCGCGGCAAGGCGCGGGAA
CTGAGCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A8E0L7

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7Q778

References