Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 449453..450106 Replicon chromosome
Accession NZ_CP010397
Organism Acinetobacter baumannii strain 6200

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag RU84_RS02160 Protein ID WP_039244281.1
Coordinates 449717..450106 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag RU84_RS02155 Protein ID WP_001288211.1
Coordinates 449453..449710 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RU84_RS02135 444969..445976 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
RU84_RS02140 445995..446372 + 378 WP_001216380.1 50S ribosomal protein L17 -
RU84_RS02145 446554..448044 + 1491 WP_000415132.1 NAD(P)/FAD-dependent oxidoreductase -
RU84_RS02150 448093..449265 - 1173 WP_032049938.1 acyl-CoA dehydrogenase family protein -
RU84_RS02155 449453..449710 + 258 WP_001288211.1 succinate dehydrogenase assembly factor 2 Antitoxin
RU84_RS02160 449717..450106 + 390 WP_039244281.1 membrane protein Toxin
RU84_RS02165 450876..451961 + 1086 WP_000049106.1 hypothetical protein -
RU84_RS02170 452039..452605 + 567 WP_000651536.1 rhombosortase -
RU84_RS02175 452793..454988 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-80)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15663.92 Da        Isoelectric Point: 10.3057

>T52336 WP_039244281.1 NZ_CP010397:449717-450106 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILNIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

>T52336 NZ_CP010397:449717-450106 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCACGCGTCAAAATTTTAAATATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGTAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10344.80 Da        Isoelectric Point: 4.4909

>AT52336 WP_001288211.1 NZ_CP010397:449453-449710 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
YYVHG

Download         Length: 258 bp

>AT52336 NZ_CP010397:449453-449710 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
TACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References