Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1908926..1909071 Replicon chromosome
Accession NZ_CP010392
Organism Klebsiella pneumoniae strain 34618

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1908962..1909064 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1908926..1909071 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LI86_RS09455 1904056..1906116 + 2061 WP_004151449.1 oligopeptidase B -
LI86_RS09460 1906120..1906779 - 660 WP_002911407.1 exodeoxyribonuclease X -
LI86_RS09465 1906858..1907088 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LI86_RS09470 1907201..1907575 + 375 WP_023286640.1 CopC domain-containing protein YobA -
LI86_RS09475 1907579..1908448 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
LI86_RS09480 1908465..1908803 + 339 WP_016529031.1 YebY family protein -
- 1908926..1909071 - 146 - - Antitoxin
- 1908962..1909064 + 103 - - Toxin
LI86_RS30715 1909438..1909581 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LI86_RS09490 1909686..1910654 - 969 WP_074194451.1 VirK/YbjX family protein -
LI86_RS09495 1910811..1911464 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
LI86_RS09500 1911461..1911652 - 192 WP_002911395.1 YebW family protein -
LI86_RS09505 1911750..1911989 - 240 WP_002911393.1 YebV family protein -
LI86_RS09510 1912105..1913538 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T52320 NZ_CP010392:1908962-1909064 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT52320 NZ_CP010392:c1909071-1908926 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References