Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 484521..485162 Replicon chromosome
Accession NZ_CP010368
Organism Acinetobacter nosocomialis strain 6411

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag RR32_RS02330 Protein ID WP_022575951.1
Coordinates 484773..485162 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag RR32_RS02325 Protein ID WP_151276929.1
Coordinates 484521..484766 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RR32_RS02305 480023..481030 + 1008 WP_002049752.1 DNA-directed RNA polymerase subunit alpha -
RR32_RS02310 481049..481426 + 378 WP_002049717.1 50S ribosomal protein L17 -
RR32_RS02315 481608..483098 + 1491 WP_039246270.1 NAD(P)/FAD-dependent oxidoreductase -
RR32_RS02320 483147..484319 - 1173 WP_039246272.1 acyl-CoA dehydrogenase family protein -
RR32_RS02325 484521..484766 + 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
RR32_RS02330 484773..485162 + 390 WP_022575951.1 hypothetical protein Toxin
RR32_RS02335 485930..487015 + 1086 WP_002049690.1 hypothetical protein -
RR32_RS02340 487099..487665 + 567 WP_004711824.1 rhombosortase -
RR32_RS02345 487853..490048 + 2196 WP_006580689.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15637.74 Da        Isoelectric Point: 10.2623

>T52225 WP_022575951.1 NZ_CP010368:484773-485162 [Acinetobacter nosocomialis]
MVNHLNFKLKYSRFAIIFQFFIGLSLVVLFYQLLPILWWLVTVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIINYQIFIVIYFEGHKTLTSVIWFDQMPLSQWKQLKTLEKFY

Download         Length: 390 bp

>T52225 NZ_CP010368:484773-485162 [Acinetobacter nosocomialis]
TTGGTCAACCATTTGAATTTCAAACTGAAATATAGCCGTTTTGCGATTATATTTCAGTTTTTTATTGGCTTAAGTTTGGT
AGTTCTATTTTATCAACTCCTACCAATATTATGGTGGTTGGTTACGGTCAGTTTACTATTCATAAGTTTTATTTTCTTTT
TAAAGCGGCCACAGCTCGCTCAAATTGCTCATTTAGATCAAAAATTATGGTCACTTAGCTTTCATTCAGAACAAACAATT
TCTCGGGTAGAGATTTTAAAAATAATTAATTATCAGATTTTCATAGTGATCTATTTTGAAGGGCATAAGACACTAACTTC
TGTTATTTGGTTTGATCAAATGCCTTTATCTCAGTGGAAACAACTTAAAACTTTAGAAAAATTTTATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT52225 WP_151276929.1 NZ_CP010368:484521-484766 [Acinetobacter nosocomialis]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT52225 NZ_CP010368:484521-484766 [Acinetobacter nosocomialis]
ATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTTTGACCCGTATGT
GAAAAATTATTATTTAAAGGCAGATCCAGCAGAAAAAGCATTATTTGCTGAATTGGTAGAGCAGGAAGATCCTGATTTAC
TTGACTGGTTTATGGAAGTATCTGAACCGCCGCGTACAGAATTACGTGATTTTATTCATAAATTAAAGCATTATGTTCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References