Detailed information of TA system TA051984

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 3137535..3138037
• Replicon: chromosome
• Accession: NZ_CP010311
• Organism: Geoalkalibacter subterraneus strain Red1

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: GSUB_RS14625
• Protein ID: WP_200890148.1
• Coordinates: 3137535..3137768 (-)
• Length: 78 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: GSUB_RS19175
• Protein ID: WP_052464975.1
• Coordinates: 3137759..3138037 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GSUB_RS14605	3133150..3134088	-	939	WP_040201448.1	transposase	-
GSUB_RS14610	3134438..3135109	-	672	WP_040201449.1	response regulator	-
GSUB_RS14615	3135106..3136521	-	1416	WP_040201450.1	HAMP domain-containing protein	-
GSUB_RS14620	3136909..3137424	+	516	WP_040201452.1	Spy/CpxP family protein refolding chaperone	-
GSUB_RS14625	3137535..3137768	-	234	WP_200890148.1	DUF86 domain-containing protein	Toxin
GSUB_RS19175	3137759..3138037	-	279	WP_052464975.1	nucleotidyltransferase domain-containing protein	Antitoxin
GSUB_RS14635	3138300..3140393	+	2094	WP_040201453.1	SEC-C domain-containing protein	-
GSUB_RS14640	3140523..3142058	+	1536	WP_200890149.1	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (5-70)

Antitoxin

• Polymerase beta, nucleotidyltransferase (11-91)

Sequences

Toxin

Protein

• Length: 78 a.a.
• Molecular weight: 8607.04 Da
• Isoelectric Point: 9.3440

>T51984 WP_200890148.1 NZ_CP010311:c3137768-3137535 [Geoalkalibacter subterraneus]
VRVRKLGLPQESREAFALLEKAGVLDGELSVRLQAMVGFRNVAVHDDQKLNLEIVKSILEEGLQAFRRFCGVLTRTA

Nucleotide

• Length: 234 bp

>T51984 NZ_CP010311:c3137768-3137535 [Geoalkalibacter subterraneus]
GTGCGTGTGAGGAAATTGGGTCTTCCCCAGGAGAGCCGAGAGGCGTTCGCCCTGCTGGAAAAAGCCGGGGTTCTCGATGG
CGAATTATCTGTGCGTCTGCAGGCGATGGTCGGTTTTCGCAATGTCGCCGTGCATGACGATCAGAAGTTGAACCTGGAAA
TCGTGAAAAGCATATTGGAAGAGGGCTTGCAGGCTTTTCGTCGCTTCTGTGGGGTTCTGACGCGAACGGCGTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10502.14 Da
• Isoelectric Point: 7.2448

>AT51984 WP_052464975.1 NZ_CP010311:c3138037-3137759 [Geoalkalibacter subterraneus]
MDHMIVQCLREAVPRLLAVYRFGSFGTEGEHPASDLDIAFLAEASPSRVQRWRLAQEMATRFGRDVDLIDLAQATTVFRM
QVIAHGRRIWCV

Nucleotide

• Length: 279 bp

>AT51984 NZ_CP010311:c3138037-3137759 [Geoalkalibacter subterraneus]
ATGGACCACATGATTGTCCAGTGCCTGCGGGAAGCTGTGCCGCGTCTGCTGGCGGTGTATCGGTTCGGCAGTTTCGGTAC
AGAAGGGGAGCATCCGGCAAGTGATCTTGATATCGCCTTTCTGGCGGAGGCTTCCCCCAGTCGCGTGCAGCGCTGGAGAC
TGGCGCAGGAAATGGCGACCAGGTTCGGCCGGGATGTGGACCTGATCGACCTGGCGCAGGCGACGACGGTTTTTCGCATG
CAGGTGATCGCCCATGGCAGGCGCATCTGGTGCGTGTGA