Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2392333..2392604 Replicon chromosome
Accession NZ_CP010304
Organism Escherichia coli O157:H7 str. SS52

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2392371..2392474 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2392333..2392604 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SS52_RS12275 2389490..2390929 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SS52_RS12280 2391047..2391283 + 237 WP_001295499.1 DUF1480 family protein -
SS52_RS12285 2391388..2391579 + 192 WP_001296140.1 YebW family protein -
SS52_RS12290 2391580..2392236 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2392333..2392604 + 272 - - Antitoxin
- 2392371..2392474 - 104 - - Toxin
SS52_RS12300 2392632..2392973 - 342 WP_000976483.1 YebY family protein -
SS52_RS12305 2392986..2393858 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
SS52_RS12310 2393862..2394236 - 375 WP_000168751.1 CopC domain-containing protein YobA -
SS52_RS12315 2394375..2394605 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SS52_RS12320 2394707..2395363 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
SS52_RS12325 2395387..2396049 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51951 NZ_CP010304:c2392474-2392371 [Escherichia coli O157:H7 str. SS52]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51951 NZ_CP010304:2392333-2392604 [Escherichia coli O157:H7 str. SS52]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References