Detailed information of TA system TA051795

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /COG5642-COG5654
• Location: 3305587..3306587
• Replicon: chromosome
• Accession: NZ_CP010247
• Organism: Yersinia pestis Pestoides G

Toxin (Protein)

• Gene name: -
• Uniprot ID: A0A0E8XJV6
• Locus tag: CH43_RS15790
• Protein ID: WP_002210981.1
• Coordinates: 3306129..3306587 (+)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: Q66A69
• Locus tag: CH43_RS15785
• Protein ID: WP_002210982.1
• Coordinates: 3305587..3306033 (+)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CH43_RS15765	3301119..3302141	+	1023	WP_042659400.1	IS21-like element IS100 family transposase	-
CH43_RS15770	3302141..3302920	+	780	WP_001297096.1	IS21-like element IS100kyp family helper ATPase IstB	-
CH43_RS15775	3303069..3303527	+	459	WP_002213759.1	IS200/IS605-like element IS1541A family transposase	-
CH43_RS15780	3303674..3305251	-	1578	WP_002210983.1	transcriptional regulator TyrR	-
CH43_RS15785	3305587..3306033	+	447	WP_002210982.1	DUF2384 domain-containing protein	Antitoxin
CH43_RS15790	3306129..3306587	+	459	WP_002210981.1	RES family NAD+ phosphorylase	Toxin
CH43_RS15795	3306597..3307658	-	1062	WP_002210980.1	YcjF family protein	-
CH43_RS15800	3307655..3309052	-	1398	WP_011906190.1	YcjX family protein	-
CH43_RS15805	3309033..3309275	-	243	WP_002216375.1	phage shock protein PspD	-
CH43_RS15810	3309360..3309719	-	360	WP_002210977.1	envelope stress response membrane protein PspC	-
CH43_RS15815	3309719..3309946	-	228	WP_002210976.1	envelope stress response membrane protein PspB	-
CH43_RS15820	3310108..3310773	-	666	WP_002210975.1	phage shock protein PspA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (2-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 16994.38 Da
• Isoelectric Point: 4.8732

>T51795 WP_002210981.1 NZ_CP010247:3306129-3306587 [Yersinia pestis Pestoides G]
MTLYRIVMRRYLASAWTGYGAEIYGGRWNHKGHAAIYLASSISLAMLETLAHIQDSSTLSEFELFQIEISDSSIMLLQPQ
DWPTDWRSDPAPVATMDVGTEWLESESSVGLLVPSTLVPSENNLLVNPHHKDFPACLASVKPLSFVFDPRLK

Nucleotide

• Length: 459 bp

>T51795 NZ_CP010247:3306129-3306587 [Yersinia pestis Pestoides G]
ATGACGCTATACCGCATTGTTATGCGCCGCTATCTTGCATCGGCATGGACTGGTTACGGCGCTGAAATCTATGGTGGTCG
TTGGAATCATAAAGGCCATGCTGCCATCTATTTAGCCAGCAGTATTTCATTGGCTATGCTCGAAACACTGGCACATATTC
AGGACAGTTCAACACTCAGCGAATTTGAATTATTCCAAATTGAAATCAGTGACAGCAGTATTATGTTGCTACAGCCGCAG
GACTGGCCCACGGATTGGCGTAGCGATCCGGCACCGGTGGCAACGATGGATGTCGGCACCGAGTGGCTGGAATCAGAATC
CTCGGTAGGCTTACTGGTCCCGTCCACGTTGGTGCCGTCAGAAAACAACCTACTGGTCAATCCTCATCACAAAGATTTTC
CAGCGTGTTTGGCCAGCGTCAAACCGCTCTCTTTTGTCTTTGATCCACGGTTAAAATAG

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16401.94 Da
• Isoelectric Point: 9.7155

>AT51795 WP_002210982.1 NZ_CP010247:3305587-3306033 [Yersinia pestis Pestoides G]
MRAYRPNPATKMGTLWREIGLPASRGTILVDSIKMGFSVDVIDSIHLWASMPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGYRSPDSLLETETGALEVCDLIGRLEHGVFT

Nucleotide

• Length: 447 bp

>AT51795 NZ_CP010247:3305587-3306033 [Yersinia pestis Pestoides G]
ATGAGAGCGTACCGCCCAAACCCCGCGACTAAAATGGGAACGCTTTGGCGTGAAATTGGCTTACCCGCCAGCCGCGGCAC
GATATTGGTCGATAGTATCAAAATGGGGTTTTCTGTTGATGTTATCGACAGCATTCATTTATGGGCATCCATGCCTAAAG
CTGAAATATTACGTGCTACCGGTATCCCCAGCCGTAGCCTGACTCGCCGCCGCACACATGATGGCCGTTTTACGCCTGAA
GAAAGCGAGAGAATCGCACGTTTTGTCCGCGTAATGGATGCCGCTGTCGATTTGTTCGGCGGCGATAAAGGTAAAGCCAT
TACCTGGATGTCCACGCCCATCAAAGGATTGGGGTACCGCAGCCCAGACTCCTTACTGGAAACCGAAACTGGCGCACTGG
AAGTGTGTGATTTGATTGGTCGTTTGGAACACGGCGTCTTTACTTAA

Structures

Toxin

• AlphaFold DB: A0A0E8XJV6

Antitoxin

• AlphaFold DB: A0A0E8XFL1