Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4592642..4592913 Replicon chromosome
Accession NZ_CP010238
Organism Escherichia coli strain S50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4592680..4592783 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4592642..4592913 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG72_RS23960 4589799..4591238 + 1440 WP_001512833.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG72_RS23965 4591356..4591592 + 237 WP_001295499.1 DUF1480 family protein -
RG72_RS23970 4591697..4591888 + 192 WP_001296140.1 YebW family protein -
RG72_RS23975 4591889..4592545 - 657 WP_000812720.1 protein-serine/threonine phosphatase -
- 4592642..4592913 + 272 - - Antitoxin
- 4592680..4592783 - 104 - - Toxin
RG72_RS23985 4592941..4593282 - 342 WP_000976492.1 YebY family protein -
RG72_RS23990 4593295..4594167 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG72_RS23995 4594171..4594545 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG72_RS24000 4594684..4594914 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG72_RS24005 4595016..4595672 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG72_RS24010 4595696..4596358 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51698 NZ_CP010238:c4592783-4592680 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51698 NZ_CP010238:4592642-4592913 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References