Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3921992..3922263 Replicon chromosome
Accession NZ_CP010237
Organism Escherichia coli strain S43

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3922122..3922225 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3921992..3922263 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG71_RS20440 3918547..3919209 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG71_RS20445 3919233..3919889 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
RG71_RS20450 3919991..3920221 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG71_RS20455 3920360..3920734 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG71_RS20460 3920738..3921610 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
RG71_RS20465 3921623..3921964 + 342 WP_000976476.1 YebY family protein -
- 3921992..3922263 - 272 - - Antitoxin
- 3922122..3922225 + 104 - - Toxin
RG71_RS20475 3922360..3923016 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
RG71_RS20480 3923017..3923208 - 192 WP_001296140.1 YebW family protein -
RG71_RS20485 3923313..3923549 - 237 WP_001295499.1 DUF1480 family protein -
RG71_RS20490 3923667..3925106 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51673 NZ_CP010237:3922122-3922225 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51673 NZ_CP010237:c3922263-3921992 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References