Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1770061..1770332 Replicon chromosome
Accession NZ_CP010236
Organism Escherichia coli strain S42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1770099..1770202 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1770061..1770332 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG70_RS09250 1767218..1768657 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG70_RS09255 1768775..1769011 + 237 WP_001295499.1 DUF1480 family protein -
RG70_RS09260 1769116..1769307 + 192 WP_001296140.1 YebW family protein -
RG70_RS09265 1769308..1769964 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1770061..1770332 + 272 - - Antitoxin
- 1770099..1770202 - 104 - - Toxin
RG70_RS09275 1770360..1770701 - 342 WP_000976492.1 YebY family protein -
RG70_RS09280 1770714..1771586 - 873 WP_000879285.1 copper homeostasis membrane protein CopD -
RG70_RS09285 1771590..1771964 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG70_RS09290 1772103..1772333 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG70_RS09295 1772435..1773091 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG70_RS09300 1773115..1773777 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51643 NZ_CP010236:c1770202-1770099 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51643 NZ_CP010236:1770061-1770332 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References