Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1189577..1189848 Replicon chromosome
Accession NZ_CP010231
Organism Escherichia coli strain S30

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1189615..1189718 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1189577..1189848 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG68_RS06230 1186734..1188173 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG68_RS06235 1188291..1188527 + 237 WP_001338166.1 DUF1480 family protein -
RG68_RS06240 1188632..1188823 + 192 WP_001338167.1 YebW family protein -
RG68_RS06245 1188824..1189480 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 1189577..1189848 + 272 - - Antitoxin
- 1189615..1189718 - 104 - - Toxin
RG68_RS06255 1189876..1190217 - 342 WP_000976472.1 YebY family protein -
RG68_RS06260 1190230..1191102 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
RG68_RS06265 1191106..1191480 - 375 WP_000168747.1 CopC domain-containing protein YobA -
RG68_RS06270 1191619..1191849 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG68_RS06275 1191951..1192607 + 657 WP_073546492.1 carbon-nitrogen hydrolase family protein -
RG68_RS06280 1192631..1193293 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51582 NZ_CP010231:c1189718-1189615 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51582 NZ_CP010231:1189577-1189848 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References