Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3687045..3687316 Replicon chromosome
Accession NZ_CP010229
Organism Escherichia coli strain S10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3687175..3687278 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3687045..3687316 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG66_RS18960 3683600..3684262 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG66_RS18965 3684286..3684942 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG66_RS18970 3685044..3685274 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG66_RS18975 3685413..3685787 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG66_RS18980 3685791..3686663 + 873 WP_057687934.1 copper homeostasis membrane protein CopD -
RG66_RS18985 3686676..3687017 + 342 WP_000976472.1 YebY family protein -
- 3687045..3687316 - 272 - - Antitoxin
- 3687175..3687278 + 104 - - Toxin
RG66_RS18995 3687413..3688069 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
RG66_RS19000 3688070..3688261 - 192 WP_001296140.1 YebW family protein -
RG66_RS19005 3688366..3688602 - 237 WP_001295499.1 DUF1480 family protein -
RG66_RS19010 3688720..3690159 - 1440 WP_077897026.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51547 NZ_CP010229:3687175-3687278 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51547 NZ_CP010229:c3687316-3687045 [Escherichia coli]
AAAGTAAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References