Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1371434..1371668 Replicon chromosome
Accession NZ_CP010221
Organism Escherichia coli strain M19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1371564..1371667 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1371434..1371668 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG63_RS06965 1367989..1368651 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG63_RS06970 1368675..1369331 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG63_RS06975 1369433..1369663 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG63_RS06980 1369802..1370176 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG63_RS06985 1370180..1371052 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG63_RS06990 1371065..1371406 + 342 WP_000976492.1 YebY family protein -
- 1371434..1371668 - 235 - - Antitoxin
- 1371564..1371667 + 104 - - Toxin
RG63_RS07000 1371799..1372875 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
RG63_RS07005 1372841..1373122 - 282 WP_001311878.1 excisionase -
RG63_RS07010 1373229..1373417 - 189 WP_001356607.1 DUF1187 family protein -
- 1373233..1373411 + 179 NuclAT_0 - -
- 1373233..1373411 + 179 NuclAT_0 - -
- 1373233..1373411 + 179 NuclAT_0 - -
- 1373233..1373411 + 179 NuclAT_0 - -
RG63_RS07015 1373410..1373604 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
RG63_RS07020 1373661..1374470 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1365932..1427186 61254


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51463 NZ_CP010221:1371564-1371667 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT51463 NZ_CP010221:c1371668-1371434 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References