Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 2165147..2165381 | Replicon | chromosome |
Accession | NZ_CP010213 | ||
Organism | Escherichia coli strain M15 |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 2165277..2165380 (+) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 2165147..2165381 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RG61_RS11140 | 2161702..2162364 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
RG61_RS11145 | 2162388..2163044 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein | - |
RG61_RS11150 | 2163146..2163376 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
RG61_RS11155 | 2163515..2163889 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
RG61_RS11160 | 2163893..2164765 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
RG61_RS11165 | 2164778..2165119 | + | 342 | WP_000976492.1 | YebY family protein | - |
- | 2165147..2165381 | - | 235 | - | - | Antitoxin |
- | 2165277..2165380 | + | 104 | - | - | Toxin |
RG61_RS11175 | 2165512..2166588 | - | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
RG61_RS11180 | 2166554..2166835 | - | 282 | WP_001311878.1 | excisionase | - |
RG61_RS11185 | 2166942..2167130 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
- | 2166946..2167124 | + | 179 | NuclAT_0 | - | - |
- | 2166946..2167124 | + | 179 | NuclAT_0 | - | - |
- | 2166946..2167124 | + | 179 | NuclAT_0 | - | - |
- | 2166946..2167124 | + | 179 | NuclAT_0 | - | - |
RG61_RS11190 | 2167123..2167317 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
RG61_RS11195 | 2167374..2168183 | - | 810 | WP_000166317.1 | recombination protein RecT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2157738..2231182 | 73444 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T51393 NZ_CP010213:2165277-2165380 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT51393 NZ_CP010213:c2165381-2165147 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT