Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2165147..2165381 Replicon chromosome
Accession NZ_CP010213
Organism Escherichia coli strain M15

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2165277..2165380 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2165147..2165381 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG61_RS11140 2161702..2162364 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG61_RS11145 2162388..2163044 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG61_RS11150 2163146..2163376 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG61_RS11155 2163515..2163889 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG61_RS11160 2163893..2164765 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG61_RS11165 2164778..2165119 + 342 WP_000976492.1 YebY family protein -
- 2165147..2165381 - 235 - - Antitoxin
- 2165277..2165380 + 104 - - Toxin
RG61_RS11175 2165512..2166588 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
RG61_RS11180 2166554..2166835 - 282 WP_001311878.1 excisionase -
RG61_RS11185 2166942..2167130 - 189 WP_001356607.1 DUF1187 family protein -
- 2166946..2167124 + 179 NuclAT_0 - -
- 2166946..2167124 + 179 NuclAT_0 - -
- 2166946..2167124 + 179 NuclAT_0 - -
- 2166946..2167124 + 179 NuclAT_0 - -
RG61_RS11190 2167123..2167317 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
RG61_RS11195 2167374..2168183 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2157738..2231182 73444


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51393 NZ_CP010213:2165277-2165380 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT51393 NZ_CP010213:c2165381-2165147 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References