Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 411980..412251 Replicon chromosome
Accession NZ_CP010200
Organism Escherichia coli strain M10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 412018..412121 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 411980..412251 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG59_RS02120 409137..410576 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG59_RS02125 410694..410930 + 237 WP_001295499.1 DUF1480 family protein -
RG59_RS02130 411035..411226 + 192 WP_001296140.1 YebW family protein -
RG59_RS02135 411227..411883 - 657 WP_000812735.1 protein-serine/threonine phosphatase -
- 411980..412251 + 272 - - Antitoxin
- 412018..412121 - 104 - - Toxin
RG59_RS02150 412279..412620 - 342 WP_000976472.1 YebY family protein -
RG59_RS02155 412633..413505 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
RG59_RS02160 413509..413883 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG59_RS02165 414022..414252 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG59_RS02170 414354..415010 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG59_RS02175 415034..415696 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51325 NZ_CP010200:c412121-412018 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51325 NZ_CP010200:411980-412251 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References