Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1829945..1830179 Replicon chromosome
Accession NZ_CP010196
Organism Escherichia coli strain M9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1829946..1830049 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1829945..1830179 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG58_RS09700 1827143..1827952 + 810 WP_000166317.1 recombination protein RecT -
RG58_RS09705 1828009..1828203 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
RG58_RS09710 1828196..1828384 + 189 WP_001356607.1 DUF1187 family protein -
- 1828202..1828380 - 179 NuclAT_0 - -
- 1828202..1828380 - 179 NuclAT_0 - -
- 1828202..1828380 - 179 NuclAT_0 - -
- 1828202..1828380 - 179 NuclAT_0 - -
RG58_RS09715 1828491..1828772 + 282 WP_001311878.1 excisionase -
RG58_RS09720 1828738..1829814 + 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
- 1829945..1830179 + 235 - - Antitoxin
- 1829946..1830049 - 104 - - Toxin
RG58_RS09730 1830207..1830548 - 342 WP_000976492.1 YebY family protein -
RG58_RS09735 1830561..1831433 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG58_RS09740 1831437..1831811 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG58_RS09745 1831950..1832180 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG58_RS09750 1832282..1832938 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG58_RS09755 1832962..1833624 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1771753..1835688 63935


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51300 NZ_CP010196:c1830049-1829946 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT51300 NZ_CP010196:1829945-1830179 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References