Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3517992..3518263 Replicon chromosome
Accession NZ_CP010191
Organism Escherichia coli strain M8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3518122..3518225 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3517992..3518263 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG57_RS18105 3514547..3515209 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG57_RS18110 3515233..3515889 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG57_RS18115 3515991..3516221 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG57_RS18120 3516360..3516734 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG57_RS18125 3516738..3517610 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
RG57_RS18130 3517623..3517964 + 342 WP_000976472.1 YebY family protein -
- 3517992..3518263 - 272 - - Antitoxin
- 3518122..3518225 + 104 - - Toxin
RG57_RS18140 3518360..3519016 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
RG57_RS18145 3519017..3519208 - 192 WP_001296140.1 YebW family protein -
RG57_RS18150 3519313..3519549 - 237 WP_001295499.1 DUF1480 family protein -
RG57_RS18155 3519667..3521106 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51277 NZ_CP010191:3518122-3518225 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51277 NZ_CP010191:c3518263-3517992 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References