Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4239451..4239722 Replicon chromosome
Accession NZ_CP010183
Organism Escherichia coli strain M3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4239581..4239684 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4239451..4239722 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG55_RS22235 4236006..4236668 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG55_RS22240 4236692..4237348 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG55_RS22245 4237450..4237680 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG55_RS22250 4237819..4238193 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG55_RS22255 4238197..4239069 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
RG55_RS22260 4239082..4239423 + 342 WP_000976472.1 YebY family protein -
- 4239451..4239722 - 272 - - Antitoxin
- 4239581..4239684 + 104 - - Toxin
RG55_RS22270 4239819..4240475 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
RG55_RS22275 4240476..4240667 - 192 WP_001296140.1 YebW family protein -
RG55_RS22280 4240772..4241008 - 237 WP_001295499.1 DUF1480 family protein -
RG55_RS22285 4241126..4242565 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51226 NZ_CP010183:4239581-4239684 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT51226 NZ_CP010183:c4239722-4239451 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ATGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References