Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2208064..2208332 Replicon chromosome
Accession NZ_CP010170
Organism Escherichia coli strain H6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2208191..2208294 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2208064..2208332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG48_RS11455 2204617..2205279 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG48_RS11460 2205303..2205959 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
RG48_RS11465 2206061..2206291 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG48_RS11470 2206430..2206804 + 375 WP_000168739.1 CopC domain-containing protein YobA -
RG48_RS11475 2206808..2207680 + 873 WP_000879277.1 copper homeostasis membrane protein CopD -
RG48_RS11480 2207693..2208034 + 342 WP_001515445.1 YebY family protein -
- 2208064..2208332 - 269 - - Antitoxin
- 2208191..2208294 + 104 - - Toxin
RG48_RS11490 2208429..2209085 + 657 WP_001515444.1 protein-serine/threonine phosphatase -
RG48_RS11495 2209086..2209277 - 192 WP_001296140.1 YebW family protein -
RG48_RS11500 2209382..2209618 - 237 WP_001295499.1 DUF1480 family protein -
RG48_RS11505 2209736..2211175 - 1440 WP_024189843.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T51043 NZ_CP010170:2208191-2208294 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT51043 NZ_CP010170:c2208332-2208064 [Escherichia coli]
AAAGTCAGCGAAGGGAATGTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References