Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2173478..2173749 Replicon chromosome
Accession NZ_CP010163
Organism Escherichia coli strain H2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2173608..2173711 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2173478..2173749 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG45_RS11730 2170033..2170695 - 663 WP_073511840.1 exodeoxyribonuclease X -
RG45_RS11735 2170719..2171375 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
RG45_RS11740 2171477..2171707 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG45_RS11745 2171846..2172220 + 375 WP_000255065.1 CopC domain-containing protein YobA -
RG45_RS11750 2172224..2173096 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
RG45_RS11755 2173109..2173450 + 342 WP_000976472.1 YebY family protein -
- 2173478..2173749 - 272 - - Antitoxin
- 2173608..2173711 + 104 - - Toxin
RG45_RS11765 2173846..2174502 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
RG45_RS11770 2174503..2174694 - 192 WP_001338167.1 YebW family protein -
RG45_RS11775 2174799..2175035 - 237 WP_001338166.1 DUF1480 family protein -
RG45_RS11780 2175153..2176592 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2165292..2176598 11306


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50975 NZ_CP010163:2173608-2173711 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50975 NZ_CP010163:c2173749-2173478 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References