Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2182611..2182879 Replicon chromosome
Accession NZ_CP010157
Organism Escherichia coli strain D10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2182739..2182841 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2182611..2182879 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG43_RS11370 2179164..2179826 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG43_RS11375 2179850..2180506 - 657 WP_000011673.1 carbon-nitrogen hydrolase family protein -
RG43_RS11380 2180608..2180838 - 231 WP_000916759.1 DNA polymerase III subunit theta -
RG43_RS11385 2180977..2181351 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG43_RS11390 2181355..2182227 + 873 WP_000879316.1 copper homeostasis membrane protein CopD -
RG43_RS11395 2182240..2182581 + 342 WP_000976472.1 YebY family protein -
- 2182611..2182879 - 269 - - Antitoxin
- 2182739..2182841 + 103 - - Toxin
RG43_RS11410 2182976..2183632 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
RG43_RS11415 2183633..2183824 - 192 WP_001317886.1 YebW family protein -
RG43_RS11420 2183929..2184165 - 237 WP_001295499.1 DUF1480 family protein -
RG43_RS11425 2184283..2185722 - 1440 WP_001317885.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2143022..2199430 56408


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T50919 NZ_CP010157:2182739-2182841 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT50919 NZ_CP010157:c2182879-2182611 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References