Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2514007..2514278 Replicon chromosome
Accession NZ_CP010152
Organism Escherichia coli strain D9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2514045..2514148 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2514007..2514278 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG42_RS13215 2511164..2512603 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG42_RS13220 2512721..2512957 + 237 WP_001295499.1 DUF1480 family protein -
RG42_RS13225 2513062..2513253 + 192 WP_000457842.1 YebW family protein -
RG42_RS13230 2513254..2513910 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2514007..2514278 + 272 - - Antitoxin
- 2514045..2514148 - 104 - - Toxin
RG42_RS13240 2514306..2514647 - 342 WP_000976476.1 YebY family protein -
RG42_RS13245 2514660..2515532 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
RG42_RS13250 2515536..2515910 - 375 WP_000168747.1 CopC domain-containing protein YobA -
RG42_RS13255 2516049..2516279 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG42_RS13260 2516381..2517037 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG42_RS13265 2517061..2517723 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50892 NZ_CP010152:c2514148-2514045 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50892 NZ_CP010152:2514007-2514278 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References