Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1294988..1295256 Replicon chromosome
Accession NZ_CP010151
Organism Escherichia coli strain D8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1295116..1295218 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1294988..1295256 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG41_RS06385 1291542..1292204 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG41_RS06390 1292227..1292883 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
RG41_RS06395 1292985..1293215 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG41_RS06400 1293354..1293728 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG41_RS06405 1293732..1294604 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
RG41_RS06410 1294617..1294958 + 342 WP_000977376.1 YebY family protein -
- 1294988..1295256 - 269 - - Antitoxin
- 1295116..1295218 + 103 - - Toxin
RG41_RS06425 1295353..1296009 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
RG41_RS06430 1296010..1296201 - 192 WP_001296140.1 YebW family protein -
RG41_RS06435 1296306..1296542 - 237 WP_001295499.1 DUF1480 family protein -
RG41_RS06440 1296660..1298099 - 1440 WP_001467894.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T50856 NZ_CP010151:1295116-1295218 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT50856 NZ_CP010151:c1295256-1294988 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References