Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4174225..4174496 Replicon chromosome
Accession NZ_CP010148
Organism Escherichia coli strain D6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4174355..4174458 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4174225..4174496 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG39_RS21435 4170780..4171442 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG39_RS21440 4171466..4172122 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG39_RS21445 4172224..4172454 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG39_RS21450 4172593..4172967 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG39_RS21455 4172971..4173843 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
RG39_RS21460 4173856..4174197 + 342 WP_000976472.1 YebY family protein -
- 4174225..4174496 - 272 - - Antitoxin
- 4174355..4174458 + 104 - - Toxin
RG39_RS21475 4174593..4175249 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
RG39_RS21480 4175250..4175441 - 192 WP_001296140.1 YebW family protein -
RG39_RS21485 4175546..4175782 - 237 WP_001295499.1 DUF1480 family protein -
RG39_RS21490 4175900..4177339 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50812 NZ_CP010148:4174355-4174458 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50812 NZ_CP010148:c4174496-4174225 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References