Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1214484..1214755 Replicon chromosome
Accession NZ_CP010145
Organism Escherichia coli strain D5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1214522..1214625 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1214484..1214755 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG38_RS06390 1211641..1213080 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG38_RS06395 1213198..1213434 + 237 WP_001295499.1 DUF1480 family protein -
RG38_RS06400 1213539..1213730 + 192 WP_001296140.1 YebW family protein -
RG38_RS06405 1213731..1214387 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1214484..1214755 + 272 - - Antitoxin
- 1214522..1214625 - 104 - - Toxin
RG38_RS06415 1214783..1215124 - 342 WP_000976472.1 YebY family protein -
RG38_RS06420 1215137..1216009 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
RG38_RS06425 1216013..1216387 - 375 WP_000204699.1 CopC domain-containing protein YobA -
RG38_RS06430 1216526..1216756 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG38_RS06435 1216858..1217514 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
RG38_RS06440 1217538..1218200 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50769 NZ_CP010145:c1214625-1214522 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50769 NZ_CP010145:1214484-1214755 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References