Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2346284..2346555 Replicon chromosome
Accession NZ_CP010143
Organism Escherichia coli strain D4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2346322..2346425 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2346284..2346555 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG37_RS12370 2343441..2344880 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RG37_RS12375 2344998..2345234 + 237 WP_001295499.1 DUF1480 family protein -
RG37_RS12380 2345339..2345530 + 192 WP_000457842.1 YebW family protein -
RG37_RS12385 2345531..2346187 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2346284..2346555 + 272 - - Antitoxin
- 2346322..2346425 - 104 - - Toxin
RG37_RS12395 2346583..2346924 - 342 WP_000976476.1 YebY family protein -
RG37_RS12400 2346937..2347809 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
RG37_RS12405 2347813..2348187 - 375 WP_000168747.1 CopC domain-containing protein YobA -
RG37_RS12410 2348326..2348556 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RG37_RS12415 2348658..2349314 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG37_RS12420 2349338..2350000 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50748 NZ_CP010143:c2346425-2346322 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50748 NZ_CP010143:2346284-2346555 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References