50675

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2207981..2208252 Replicon chromosome
Accession NZ_CP010137
Organism Escherichia coli strain D2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2208111..2208214 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2207981..2208252 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG35_RS11295 2204537..2205199 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG35_RS11300 2205223..2205879 - 657 WP_073544200.1 carbon-nitrogen hydrolase family protein -
RG35_RS11305 2205981..2206211 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG35_RS11310 2206350..2206724 + 375 WP_000168747.1 CopC domain-containing protein YobA -
RG35_RS11315 2206728..2207600 + 873 WP_000879294.1 copper homeostasis membrane protein CopD -
RG35_RS11320 2207613..2207954 + 342 WP_000976472.1 YebY family protein -
- 2207981..2208252 - 272 - - Antitoxin
- 2208111..2208214 + 104 - - Toxin
RG35_RS11330 2208349..2209005 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
RG35_RS11335 2209006..2209197 - 192 WP_001296140.1 YebW family protein -
RG35_RS11340 2209302..2209538 - 237 WP_001295499.1 DUF1480 family protein -
RG35_RS11345 2209656..2211095 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50675 NZ_CP010137:2208111-2208214 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50675 NZ_CP010137:c2208252-2207981 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References