Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4590128..4590399 Replicon chromosome
Accession NZ_CP010133
Organism Escherichia coli strain C11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4590258..4590361 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4590128..4590399 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG33_RS23655 4586683..4587345 - 663 WP_000944256.1 exodeoxyribonuclease X -
RG33_RS23660 4587369..4588025 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
RG33_RS23665 4588127..4588357 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG33_RS23670 4588496..4588870 + 375 WP_000204699.1 CopC domain-containing protein YobA -
RG33_RS23675 4588874..4589746 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
RG33_RS23680 4589759..4590100 + 342 WP_000976492.1 YebY family protein -
- 4590128..4590399 - 272 - - Antitoxin
- 4590258..4590361 + 104 - - Toxin
RG33_RS23690 4590496..4591152 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
RG33_RS23695 4591153..4591344 - 192 WP_001296140.1 YebW family protein -
RG33_RS23700 4591449..4591685 - 237 WP_001295499.1 DUF1480 family protein -
RG33_RS23705 4591803..4593242 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50630 NZ_CP010133:4590258-4590361 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50630 NZ_CP010133:c4590399-4590128 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References