Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2392776..2393047 Replicon chromosome
Accession NZ_CP010121
Organism Escherichia coli strain C4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2392906..2393009 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2392776..2393047 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG27_RS12240 2389331..2389993 - 663 WP_073461879.1 exodeoxyribonuclease X -
RG27_RS12245 2390017..2390673 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
RG27_RS12250 2390775..2391005 - 231 WP_000916763.1 DNA polymerase III subunit theta -
RG27_RS12255 2391144..2391518 + 375 WP_000168743.1 CopC domain-containing protein YobA -
RG27_RS12260 2391522..2392394 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
RG27_RS12265 2392407..2392748 + 342 WP_000976481.1 YebY family protein -
- 2392776..2393047 - 272 - - Antitoxin
- 2392906..2393009 + 104 - - Toxin
RG27_RS12280 2393144..2393800 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
RG27_RS12285 2393801..2393992 - 192 WP_001296140.1 YebW family protein -
RG27_RS12290 2394097..2394333 - 237 WP_001295499.1 DUF1480 family protein -
RG27_RS12295 2394451..2395890 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2385467..2395896 10429


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50458 NZ_CP010121:2392906-2393009 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50458 NZ_CP010121:c2393047-2392776 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References