Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3212231..3212502 Replicon chromosome
Accession NZ_CP010116
Organism Escherichia coli strain C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3212269..3212372 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3212231..3212502 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RC72_RS16325 3209388..3210827 + 1440 WP_049068043.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RC72_RS16330 3210945..3211181 + 237 WP_001295499.1 DUF1480 family protein -
RC72_RS16335 3211286..3211477 + 192 WP_001296140.1 YebW family protein -
RC72_RS16340 3211478..3212134 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 3212231..3212502 + 272 - - Antitoxin
- 3212269..3212372 - 104 - - Toxin
RC72_RS16355 3212530..3212871 - 342 WP_000976472.1 YebY family protein -
RC72_RS16360 3212884..3213756 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
RC72_RS16365 3213760..3214134 - 375 WP_000168747.1 CopC domain-containing protein YobA -
RC72_RS16370 3214273..3214503 + 231 WP_000916763.1 DNA polymerase III subunit theta -
RC72_RS16375 3214605..3215261 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
RC72_RS16380 3215285..3215947 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3196391..3236287 39896


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T50375 NZ_CP010116:c3212372-3212269 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT50375 NZ_CP010116:3212231-3212502 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References