Detailed information of TA system TA050270

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-TIGR02293
• Location: 460626..461635
• Replicon: chromosome
• Accession: NZ_CP010025
• Organism: Paraburkholderia fungorum strain ATCC BAA-463

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: OI25_RS04520
• Protein ID: WP_046565159.1
• Coordinates: 461156..461635 (+)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: OI25_RS04515
• Protein ID: WP_052719590.1
• Coordinates: 460626..461159 (+)
• Length: 178 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OI25_RS43110	456090..456266	+	177	WP_158380663.1	hypothetical protein	-
OI25_RS04490	456318..457205	+	888	WP_046565152.1	hypothetical protein	-
OI25_RS04495	457297..457827	+	531	WP_046565154.1	hypothetical protein	-
OI25_RS04500	458139..459386	+	1248	WP_158380664.1	hypothetical protein	-
OI25_RS04510	460176..460487	-	312	WP_046565157.1	hypothetical protein	-
OI25_RS04515	460626..461159	+	534	WP_052719590.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
OI25_RS04520	461156..461635	+	480	WP_046565159.1	RES family NAD+ phosphorylase	Toxin
OI25_RS04525	461709..462056	+	348	WP_046565160.1	hypothetical protein	-
OI25_RS42495	462366..462554	+	189	WP_137954098.1	hypothetical protein	-
OI25_RS04535	462581..463273	+	693	WP_046565164.1	SOS response-associated peptidase	-
OI25_RS04540	463294..464388	+	1095	WP_046565166.1	hypothetical protein	-
OI25_RS04545	464433..464861	+	429	WP_046565594.1	hypothetical protein	-
OI25_RS43115	465434..465964	-	531	WP_045706996.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-145)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (49-110)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17220.77 Da
• Isoelectric Point: 6.4612

>T50270 WP_046565159.1 NZ_CP010025:461156-461635 [Paraburkholderia fungorum]
MTVAIWRIATDTPDYTADDLSGEGAKRTGGRWNRAGMPVLYCASSIALACLETVVHWNAGGLPLNRYLVRIDVPDDVWNA
ATIVPADAGPVGWDAIPEGKVSLDLGDGWISAKKSALLLVPSVIVPEEFNALVNPLHPDAATLTATKRRKWLYDSRIKK

Nucleotide

• Length: 480 bp

>T50270 NZ_CP010025:461156-461635 [Paraburkholderia fungorum]
ATGACGGTGGCGATCTGGCGGATCGCCACTGACACTCCCGATTACACCGCCGATGACCTGTCTGGCGAGGGCGCCAAGCG
AACCGGGGGACGATGGAACAGGGCAGGTATGCCGGTGCTGTACTGCGCGTCGAGCATTGCGTTGGCCTGCCTTGAAACCG
TGGTGCATTGGAATGCCGGGGGCCTGCCTTTGAACAGGTATCTCGTCCGGATAGATGTGCCGGATGACGTTTGGAACGCC
GCGACGATCGTGCCGGCCGACGCGGGTCCGGTGGGTTGGGACGCCATACCTGAAGGCAAGGTAAGTCTGGACCTCGGCGA
CGGCTGGATCAGCGCGAAGAAGTCTGCGCTTTTGCTGGTGCCATCAGTGATCGTTCCGGAAGAATTCAACGCGCTTGTCA
ATCCGTTGCATCCGGACGCCGCCACGTTGACCGCGACGAAGCGGCGCAAATGGCTCTATGACAGCCGAATCAAGAAGTAG

Antitoxin

Protein

• Length: 178 a.a.
• Molecular weight: 19100.95 Da
• Isoelectric Point: 10.1630

>AT50270 WP_052719590.1 NZ_CP010025:460626-461159 [Paraburkholderia fungorum]
MTVTIQRAKRPSTRKTAAAVVAQAARPAIGRTPRTIGDFVQIYEAGPMERIELIKSGISADGLVDLATSMHTTKDQLFKR
LGLPRATVDRKARNKQNLSQEQSERVIGLMKLVGQVKTMVEQSGEPEGFDAAQWVGQWLEQANGALGGIPPAELMDTVQG
QEVISGLLAKMQSGAYA

Nucleotide

• Length: 534 bp

>AT50270 NZ_CP010025:460626-461159 [Paraburkholderia fungorum]
ATGACCGTTACTATCCAGCGCGCCAAACGACCCTCCACCCGGAAAACGGCGGCCGCCGTTGTCGCGCAGGCAGCGCGGCC
GGCCATCGGCCGCACGCCCCGAACGATCGGCGACTTCGTGCAGATTTACGAAGCGGGTCCAATGGAACGGATCGAGTTGA
TCAAAAGCGGAATCAGCGCCGATGGGCTTGTTGATCTGGCGACGTCGATGCATACGACAAAGGATCAGCTCTTCAAGCGG
CTTGGGCTTCCGCGCGCGACGGTCGACCGGAAAGCACGTAACAAGCAGAATCTCTCGCAGGAGCAGTCAGAGCGCGTCAT
TGGCCTGATGAAGCTCGTCGGCCAGGTGAAGACGATGGTCGAGCAATCGGGCGAGCCGGAAGGCTTTGACGCCGCTCAAT
GGGTTGGGCAGTGGCTTGAGCAAGCGAACGGCGCACTCGGGGGCATTCCTCCCGCCGAGCTGATGGACACGGTTCAAGGA
CAGGAAGTGATCTCCGGCCTTCTCGCTAAGATGCAGAGCGGGGCATACGCATGA