50241

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 1483717..1484923 Replicon chromosome
Accession NZ_CP010013
Organism Helicobacter pylori strain Hp238

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag OI67_RS07235 Protein ID WP_039704989.1
Coordinates 1483717..1484496 (-) Length 260 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag OI67_RS07240 Protein ID WP_039704990.1
Coordinates 1484486..1484923 (-) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI67_RS07225 1481053..1482213 + 1161 WP_039704987.1 L-seryl-tRNA(Sec) selenium transferase -
OI67_RS07230 1482301..1483488 + 1188 WP_039704988.1 transcription termination/antitermination protein NusA -
OI67_RS07235 1483717..1484496 - 780 WP_039704989.1 hypothetical protein Toxin
OI67_RS07240 1484486..1484923 - 438 WP_039704990.1 SocA family protein Antitoxin
OI67_RS07245 1485147..1486773 - 1627 Protein_1390 RNA-directed DNA polymerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(24-119)


Sequences

Toxin        


Download         Length: 260 a.a.        Molecular weight: 30338.45 Da        Isoelectric Point: 6.7319

>T50241 WP_039704989.1 NZ_CP010013:c1484496-1483717 [Helicobacter pylori]
METKEEDKDKKLEEIIVLLCEEGDLSSQKDQIIKDLKEIYEGEYKHKYSKITTIILNSTRDKEQAFMMLTQNIKTLKEIQ
DNKEVESIKPKLEKLYDHMNLECIRLQDFDEKMSRVKDISIKLDNLNKNYKKLSEELNKQQTQYITILGIFASIVLTFVG
GLAFSTSVLSNIDKANAYRLVFVMAFIALFFGNILYLLFSFLSKISLSSKISLSEEEKDKQENFFKKPIFWFNLMVTILF
VIGFFGELHIIQRLVSKYL

Download         Length: 780 bp

>T50241 NZ_CP010013:c1484496-1483717 [Helicobacter pylori]
ATGGAAACTAAAGAAGAGGATAAAGATAAAAAGCTAGAAGAAATTATTGTATTGCTGTGCGAAGAGGGGGATTTGTCTAG
TCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATGAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACACTCAAAGAGATTCAA
GATAACAAAGAAGTTGAAAGCATTAAACCAAAATTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATTAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATATTTCTATAAAGTTAGATAATCTAAATAAAAACTATAAAAAATTAA
GCGAAGAATTGAATAAGCAACAAACACAATACATAACAATTTTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTTGGG
GGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTTTAT
AGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCATCAAAAATATCCTTAT
CAGAAGAGGAAAAAGATAAACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTAATGGTTACAATTCTATTT
GTGATTGGTTTTTTTGGAGAATTGCATATAATACAAAGATTAGTTTCTAAATATCTTTGA

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 17265.37 Da        Isoelectric Point: 5.7911

>AT50241 WP_039704990.1 NZ_CP010013:c1484923-1484486 [Helicobacter pylori]
MVNTLELAKYILKRSNKELSNLELQKTLYFTELDYIKKFDKHLVSDDFEAWKYGPVAREVYYEYRNYGASSIDKPKEETL
SQSLREDELETINRSIEKCNEKSYWDLVKESHKEDGAWHKSFKEDRKEIISKDLIKQEAKQANGN

Download         Length: 438 bp

>AT50241 NZ_CP010013:c1484923-1484486 [Helicobacter pylori]
ATGGTCAATACTTTGGAATTAGCAAAATATATTCTTAAGCGTTCCAACAAAGAATTGAGCAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATTAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATATG
GGCCTGTTGCAAGAGAAGTGTATTATGAATACCGCAATTATGGTGCCAGTTCTATTGACAAACCCAAAGAAGAAACGCTC
TCACAAAGTCTTAGAGAAGATGAACTTGAAACCATCAATCGCTCCATAGAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGCGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References