Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 931479..932103 Replicon chromosome
Accession NZ_CP010013
Organism Helicobacter pylori strain Hp238

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OI67_RS04490 Protein ID WP_039704652.1
Coordinates 931479..931745 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OI67_RS04495 Protein ID WP_039704653.1
Coordinates 931726..932103 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI67_RS04465 926939..928078 - 1140 WP_200885218.1 glycosyltransferase family 8 protein -
OI67_RS04470 928149..928916 - 768 WP_039704649.1 ABC transporter ATP-binding protein -
OI67_RS04475 928916..929896 - 981 WP_000921482.1 iron ABC transporter permease -
OI67_RS04480 929889..930731 - 843 WP_039704650.1 SDR family oxidoreductase -
OI67_RS04485 930872..931396 + 525 WP_039704651.1 acyl-CoA thioesterase -
OI67_RS04490 931479..931745 - 267 WP_039704652.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
OI67_RS04495 931726..932103 - 378 WP_039704653.1 hypothetical protein Antitoxin
OI67_RS04505 932720..934945 - 2226 WP_039704655.1 Hop family adhesin BabA -
OI67_RS04520 935355..935978 + 624 WP_144245625.1 hypothetical protein -
OI67_RS04525 935929..937041 - 1113 WP_039704656.1 hydrogenase formation protein HypD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10347.22 Da        Isoelectric Point: 9.6292

>T50240 WP_039704652.1 NZ_CP010013:c931745-931479 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKTDILLVYLVKDDELILLR
LGSHSELF

Download         Length: 267 bp

>T50240 NZ_CP010013:c931745-931479 [Helicobacter pylori]
GTGTTGAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATAAGGTCATTCTGTCTTTGAGAAAAAAAGAACCGCTAGACCCACAATTTCAAGATCATGCTTTAAAGGGAAAGTGGA
AACCTTTTAGGGAATGCCATATCAAAACTGACATTTTGCTTGTGTATTTAGTGAAAGATGATGAGCTGATTTTGTTAAGA
CTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14656.64 Da        Isoelectric Point: 9.0131

>AT50240 WP_039704653.1 NZ_CP010013:c932103-931726 [Helicobacter pylori]
MPNSPTKKDYTRYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNGLLQKISQAFDDKRDCCL
GHKIPNIQTQQAMRDALNKETDLIVEDFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT50240 NZ_CP010013:c932103-931726 [Helicobacter pylori]
ATGCCTAATTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTAATCAATCAATTAGAGCA
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGGACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTG
GGGCACAAGATCCCAAACATTCAAACGCAACAAGCCATGAGAGATGCGCTCAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGTGATGAAAGAAAAAGGGCGTTAGGTGTTGAAACTCAACCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References