Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3725580..3726252 Replicon chromosome
Accession NZ_CP009997
Organism Yersinia kristensenii strain Y231

Toxin (Protein)


Gene name cptA Uniprot ID A0A386HHD1
Locus tag CH54_RS16795 Protein ID WP_038631074.1
Coordinates 3725827..3726252 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A386HHJ6
Locus tag CH54_RS16790 Protein ID WP_038631072.1
Coordinates 3725580..3725846 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH54_RS16770 3721971..3722720 + 750 WP_038631064.1 SDR family oxidoreductase -
CH54_RS16775 3722733..3723335 - 603 WP_038631066.1 HD domain-containing protein -
CH54_RS16780 3723590..3724273 + 684 WP_038631068.1 hemolysin III family protein -
CH54_RS16785 3724322..3725314 - 993 WP_038631070.1 tRNA-modifying protein YgfZ -
CH54_RS16790 3725580..3725846 + 267 WP_038631072.1 FAD assembly factor SdhE Antitoxin
CH54_RS16795 3725827..3726252 + 426 WP_038631074.1 protein YgfX Toxin
CH54_RS16800 3726252..3726950 + 699 WP_038631076.1 two-component system response regulator CreB -
CH54_RS16805 3726961..3728388 + 1428 WP_038631078.1 two-component system sensor histidine kinase CreC -
CH54_RS16810 3728481..3729902 + 1422 WP_038631080.1 cell envelope integrity protein CreD -
CH54_RS16815 3729976..3730494 - 519 WP_038631082.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16459.32 Da        Isoelectric Point: 10.1175

>T50238 WP_038631074.1 NZ_CP009997:3725827-3726252 [Yersinia kristensenii]
VAQWRCDLRVSWHTQLFSLLAHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNIKSCQGEIRLKPGNVVLWKRH
EWVVVKQPWITRYGVLLSLQQTSNRSTRKRLWLAADSMPEEEWRQLCLLLRHSFGSDEGIN

Download         Length: 426 bp

>T50238 NZ_CP009997:3725827-3726252 [Yersinia kristensenii]
GTGGCCCAGTGGCGATGTGACCTGCGGGTATCCTGGCACACTCAACTCTTCTCCTTATTAGCGCATGGCGTTTTGGTGAT
ACTTACATTGGTTGCGCCTTGGCCTCAGGGCTATACCGCACTGTGGTTAGTATTACTGACGCTGGTGGTGTTTGAGTGTA
TCCGCAGCCAGAAAAACATTAAGTCTTGTCAGGGCGAGATCAGGCTGAAACCCGGTAATGTGGTGCTCTGGAAAAGGCAT
GAATGGGTGGTCGTTAAACAGCCTTGGATCACTCGCTATGGCGTGTTATTGAGTTTACAACAGACAAGCAACCGCTCAAC
CCGTAAGCGTTTATGGTTGGCTGCTGACAGTATGCCAGAAGAGGAATGGCGGCAATTATGTCTGCTGTTGCGTCATTCGT
TTGGCTCGGATGAGGGCATTAATTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.06 Da        Isoelectric Point: 5.1405

>AT50238 WP_038631072.1 NZ_CP009997:3725580-3725846 [Yersinia kristensenii]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQVFIRLLECDDPDLFNWLMNHGEPQDSELRQMVKLIQIRN
KARGPVAM

Download         Length: 267 bp

>AT50238 NZ_CP009997:3725580-3725846 [Yersinia kristensenii]
ATGGAAATCGATAATAAAGCCCGCATTCACTGGGCATGCCGTCGGGGTATGCGTGAACTGGATATCTCTATCATGCCATT
TTTCGAACATGAATATGATGGCTTGAGTGACAACGAAAAGCAGGTTTTTATTCGTTTACTTGAATGTGATGATCCAGACT
TATTTAACTGGCTGATGAATCACGGGGAGCCGCAGGATAGCGAGCTGCGCCAAATGGTCAAACTGATTCAAATACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References