Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1422944..1423479 Replicon chromosome
Accession NZ_CP009997
Organism Yersinia kristensenii strain Y231

Toxin (Protein)


Gene name relE Uniprot ID A0A386HCD1
Locus tag CH54_RS06475 Protein ID WP_038635036.1
Coordinates 1422944..1423231 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A386HCJ9
Locus tag CH54_RS06480 Protein ID WP_038635039.1
Coordinates 1423228..1423479 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH54_RS06455 1418286..1419212 + 927 WP_038635025.1 oxygen-dependent coproporphyrinogen oxidase -
CH54_RS06460 1419212..1419685 + 474 WP_038635028.1 YaiI/YqxD family protein -
CH54_RS06465 1419836..1422115 - 2280 WP_038635031.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
CH54_RS06470 1422340..1422915 - 576 WP_038635033.1 GDP-mannose pyrophosphatase NudK -
CH54_RS06475 1422944..1423231 - 288 WP_038635036.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CH54_RS06480 1423228..1423479 - 252 WP_038635039.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CH54_RS06485 1423628..1424227 - 600 WP_038635042.1 cytochrome c-type protein NapC -
CH54_RS06490 1424255..1424722 - 468 WP_038635044.1 nitrate reductase cytochrome c-type subunit -
CH54_RS06495 1424757..1427252 - 2496 WP_038635047.1 nitrate reductase catalytic subunit NapA -
CH54_RS06500 1427249..1427515 - 267 WP_019081761.1 chaperone NapD -
CH54_RS06505 1427505..1428008 - 504 WP_038635051.1 ferredoxin-type protein NapF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11215.24 Da        Isoelectric Point: 10.3200

>T50235 WP_038635036.1 NZ_CP009997:c1423231-1422944 [Yersinia kristensenii]
MIYTVKFREEALKEWHKLDKTIQQQFAKKLKKCSDNPHIESAKLRGMKDCYKIKLRSSGFRLVYEVIDDILIVAVVAVGK
RERSEVYKLASERLR

Download         Length: 288 bp

>T50235 NZ_CP009997:c1423231-1422944 [Yersinia kristensenii]
ATGATCTATACCGTTAAGTTCAGAGAAGAAGCGCTAAAGGAATGGCACAAACTGGATAAGACGATACAACAGCAGTTCGC
CAAAAAATTAAAAAAGTGCAGCGATAATCCACATATTGAGAGTGCTAAACTACGTGGGATGAAAGACTGTTACAAAATTA
AATTACGGTCCTCAGGTTTCCGACTAGTGTATGAAGTTATTGATGATATTTTGATAGTTGCTGTGGTTGCAGTAGGAAAA
AGAGAACGTAGCGAGGTTTATAAACTTGCCAGTGAAAGATTACGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9191.43 Da        Isoelectric Point: 4.1947

>AT50235 WP_038635039.1 NZ_CP009997:c1423479-1423228 [Yersinia kristensenii]
MPSVILSDTSASVSELKKNPMATVNAGAGFPVAILNRNQPAFYCVPAELYEQIMEALDDNELAKLVNERRNQPLHDIDLE
SYL

Download         Length: 252 bp

>AT50235 NZ_CP009997:c1423479-1423228 [Yersinia kristensenii]
ATGCCAAGTGTAATTTTGTCAGATACTAGCGCGAGTGTGAGTGAACTGAAGAAAAATCCCATGGCGACAGTGAATGCCGG
AGCTGGTTTCCCTGTTGCTATCCTGAACCGTAATCAACCTGCGTTTTATTGTGTGCCTGCTGAACTTTATGAACAAATAA
TGGAAGCGCTTGACGATAATGAATTGGCTAAGTTGGTTAACGAACGTCGTAACCAACCACTTCATGATATTGATTTGGAA
AGCTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References