Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1466225..1466772 Replicon chromosome
Accession NZ_CP009984
Organism Vibrio vulnificus strain FORC_009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FORC9_RS06750 Protein ID WP_060531603.1
Coordinates 1466470..1466772 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FORC9_RS06745 Protein ID WP_060531602.1
Coordinates 1466225..1466482 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC9_RS06720 1462189..1462479 + 291 WP_060531595.1 hypothetical protein -
FORC9_RS23335 1462501..1462593 + 93 WP_081036221.1 DUF3265 domain-containing protein -
FORC9_RS06725 1462639..1463163 + 525 WP_060531596.1 AAA family ATPase -
FORC9_RS23340 1463209..1463301 + 93 WP_193288685.1 DUF3265 domain-containing protein -
FORC9_RS06730 1463341..1464009 + 669 WP_060531578.1 hypothetical protein -
FORC9_RS06735 1464144..1464791 + 648 WP_060531598.1 hypothetical protein -
FORC9_RS24150 1464834..1464944 + 111 WP_155521458.1 DUF3265 domain-containing protein -
FORC9_RS06740 1465374..1466012 + 639 WP_060531600.1 class I SAM-dependent methyltransferase -
FORC9_RS06745 1466225..1466482 + 258 WP_060531602.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC9_RS06750 1466470..1466772 + 303 WP_060531603.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC9_RS23345 1466808..1466900 + 93 WP_196374716.1 DUF3265 domain-containing protein -
FORC9_RS06755 1467040..1467261 + 222 WP_005526706.1 VF530 family protein -
FORC9_RS23355 1467743..1467865 + 123 WP_081036310.1 DUF3265 domain-containing protein -
FORC9_RS06760 1467885..1468292 + 408 WP_060531605.1 NUDIX hydrolase -
FORC9_RS06765 1468510..1468860 + 351 WP_060531607.1 hypothetical protein -
FORC9_RS23360 1468875..1468967 + 93 WP_079858460.1 DUF3265 domain-containing protein -
FORC9_RS06770 1469353..1470309 - 957 WP_060531432.1 IS110 family transposase -
FORC9_RS23365 1470506..1470646 + 141 Protein_1413 DUF3265 domain-containing protein -
FORC9_RS06775 1470673..1471161 + 489 WP_060531609.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1346398..1521281 174883
- inside Integron - - 1345144..1468980 123836


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11685.61 Da        Isoelectric Point: 5.1765

>T50206 WP_060531603.1 NZ_CP009984:1466470-1466772 [Vibrio vulnificus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPLELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T50206 NZ_CP009984:1466470-1466772 [Vibrio vulnificus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGCTTGCAAACTTTCCCAGAGTCAGGTCGTATTCCAC
TCGAGCTAGAACACTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCCTGTTGAGTAAGCAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9584.04 Da        Isoelectric Point: 5.7234

>AT50206 WP_060531602.1 NZ_CP009984:1466225-1466482 [Vibrio vulnificus]
MKVELVTSLKRQATKILADLHDTKEPVLITEDGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT50206 NZ_CP009984:1466225-1466482 [Vibrio vulnificus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCGGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGGATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References