Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1426970..1427535 Replicon chromosome
Accession NZ_CP009984
Organism Vibrio vulnificus strain FORC_009

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FORC9_RS06520 Protein ID WP_060531549.1
Coordinates 1427248..1427535 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FORC9_RS06515 Protein ID WP_060531547.1
Coordinates 1426970..1427251 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC9_RS23090 1422157..1422249 + 93 WP_196374712.1 DUF3265 domain-containing protein -
FORC9_RS06490 1422276..1422725 + 450 WP_060531538.1 GNAT family N-acetyltransferase -
FORC9_RS23095 1422752..1422844 + 93 Protein_1312 DUF3265 domain-containing protein -
FORC9_RS23100 1423203..1423286 + 84 WP_081036296.1 DUF3265 domain-containing protein -
FORC9_RS06495 1423341..1423958 + 618 WP_060531540.1 HAD family phosphatase -
FORC9_RS06500 1424002..1424970 - 969 WP_081036190.1 IS30 family transposase -
FORC9_RS23105 1425001..1425189 + 189 WP_081036209.1 DUF3265 domain-containing protein -
FORC9_RS06505 1425208..1425663 + 456 WP_060531542.1 hypothetical protein -
FORC9_RS23110 1425681..1425791 + 111 WP_081036210.1 DUF3265 domain-containing protein -
FORC9_RS06510 1425801..1426298 + 498 WP_060531545.1 DUF2867 domain-containing protein -
FORC9_RS23115 1426769..1426947 + 179 Protein_1320 DUF3265 domain-containing protein -
FORC9_RS06515 1426970..1427251 + 282 WP_060531547.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC9_RS06520 1427248..1427535 + 288 WP_060531549.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC9_RS23120 1428013..1428177 + 165 WP_081036211.1 DUF3265 domain-containing protein -
FORC9_RS06525 1428164..1428697 + 534 WP_196374713.1 (d)CMP kinase -
FORC9_RS23125 1428694..1428816 + 123 WP_081036297.1 DUF3265 domain-containing protein -
FORC9_RS06530 1428841..1429320 + 480 WP_060531553.1 GNAT family N-acetyltransferase -
FORC9_RS24395 1429283..1429513 + 231 WP_196374714.1 DUF3265 domain-containing protein -
FORC9_RS06535 1429540..1429860 + 321 WP_025523864.1 DUF4160 domain-containing protein -
FORC9_RS06540 1429838..1430083 + 246 WP_025523863.1 DUF2442 domain-containing protein -
FORC9_RS24120 1430110..1430202 + 93 WP_196374721.1 DUF3265 domain-containing protein -
FORC9_RS23135 1430555..1430677 + 123 WP_081036298.1 DUF3265 domain-containing protein -
FORC9_RS06545 1430870..1431838 - 969 WP_081036190.1 IS30 family transposase -
FORC9_RS06550 1431924..1432355 + 432 WP_060531555.1 hypothetical protein -
FORC9_RS23140 1432342..1432461 + 120 WP_071652258.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1346398..1521281 174883
- inside Integron - - 1345144..1468980 123836


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10946.63 Da        Isoelectric Point: 5.0746

>T50204 WP_060531549.1 NZ_CP009984:1427248-1427535 [Vibrio vulnificus]
MKVVWSPLALQKLGDAAEFISLDNPVAAESWINEVFDKTDLLSSMPEMGRMVPELPHTNYREILFGHYRIIYSLSHEIRV
LTVRNCRQILTESDV

Download         Length: 288 bp

>T50204 NZ_CP009984:1427248-1427535 [Vibrio vulnificus]
ATGAAAGTTGTCTGGTCACCACTAGCATTACAAAAGTTAGGTGATGCAGCCGAGTTTATTTCACTGGATAACCCAGTGGC
AGCAGAAAGCTGGATTAATGAGGTTTTTGATAAAACTGATTTACTCTCAAGTATGCCTGAAATGGGGCGAATGGTTCCTG
AGTTGCCTCATACCAATTACCGCGAAATCTTGTTTGGTCACTATCGCATCATATATAGCCTTAGCCATGAAATTCGCGTT
CTCACAGTACGAAATTGTCGTCAGATACTAACGGAAAGTGACGTGTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10412.93 Da        Isoelectric Point: 5.8651

>AT50204 WP_060531547.1 NZ_CP009984:1426970-1427251 [Vibrio vulnificus]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK

Download         Length: 282 bp

>AT50204 NZ_CP009984:1426970-1427251 [Vibrio vulnificus]
ATGAGCCGTATTCACTTCGACCAAGATATTCAGCCTTTATCTGAATTTCGTGCTGGCGTAACGTCATTTATAAAACAAAT
TAACGAAACTCGCAGACCACTAGTAATCACACAACGTGGTAAAGGTGTTGCAGTTGTCCTTGATGTTGCGGAATATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGTACTGCTGAAGCACAATTAGCTTCAGGTTTAGGTGTTTCCAAT
GATGACGCTCGCGCTCAAGTGTTGGGGCGTATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References