Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1341308..1341853 Replicon chromosome
Accession NZ_CP009982
Organism Vibrio parahaemolyticus strain FORC_008

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FORC8_RS06370 Protein ID WP_053047111.1
Coordinates 1341308..1341604 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FORC8_RS06375 Protein ID WP_053047112.1
Coordinates 1341611..1341853 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC8_RS06340 1336761..1337384 + 624 WP_015296930.1 hypothetical protein -
FORC8_RS06345 1337562..1337918 + 357 WP_020198239.1 hypothetical protein -
FORC8_RS24820 1337952..1338043 + 92 Protein_1204 DUF3265 domain-containing protein -
FORC8_RS06350 1338097..1338492 + 396 WP_024699538.1 hypothetical protein -
FORC8_RS06355 1338633..1339391 + 759 WP_053047185.1 hypothetical protein -
FORC8_RS23600 1339406..1339498 + 93 WP_071936843.1 DUF3265 domain-containing protein -
FORC8_RS06360 1339529..1339963 + 435 WP_029849895.1 hypothetical protein -
FORC8_RS23605 1339983..1340075 + 93 WP_071936844.1 DUF3265 domain-containing protein -
FORC8_RS06365 1340631..1341140 + 510 WP_031849426.1 GNAT family N-acetyltransferase -
FORC8_RS25460 1341155..1341246 + 92 Protein_1211 DUF3265 domain-containing protein -
FORC8_RS06370 1341308..1341604 - 297 WP_053047111.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC8_RS06375 1341611..1341853 - 243 WP_053047112.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC8_RS06380 1342101..1342979 + 879 WP_053047187.1 DUF4145 domain-containing protein -
FORC8_RS23615 1342980..1343093 + 114 WP_071936845.1 DUF3265 domain-containing protein -
FORC8_RS06385 1343130..1343627 + 498 WP_053047113.1 hypothetical protein -
FORC8_RS23620 1343642..1343734 + 93 WP_071936820.1 DUF3265 domain-containing protein -
FORC8_RS06390 1343768..1344208 + 441 WP_053047189.1 GNAT family N-acetyltransferase -
FORC8_RS06395 1344357..1344803 + 447 WP_053047114.1 GNAT family N-acetyltransferase -
FORC8_RS06400 1344962..1345684 + 723 WP_053047191.1 hypothetical protein -
FORC8_RS06405 1345827..1346399 + 573 WP_053047193.1 hypothetical protein -
FORC8_RS23625 1346414..1346506 + 93 WP_082241140.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1277059..1383164 106105
- inside Integron - - 1277583..1354280 76697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11275.94 Da        Isoelectric Point: 9.3813

>T50203 WP_053047111.1 NZ_CP009982:c1341604-1341308 [Vibrio parahaemolyticus]
MQKNKYKLSKLAQAHLLKIKNYTVNNFSEMQWRNYKDTLLTGFQMLADNPEVGRSCDDIYPNGFHFPVGKHAAYFTKEDG
FILVVAVLGQSQLPQNHL

Download         Length: 297 bp

>T50203 NZ_CP009982:c1341604-1341308 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATATAAACTAAGTAAATTAGCTCAGGCTCATTTATTAAAAATCAAAAACTATACCGTTAATAACTT
TTCAGAGATGCAGTGGCGCAACTACAAAGATACGTTACTGACTGGATTTCAGATGCTTGCTGACAATCCGGAAGTTGGTC
GAAGTTGCGATGACATTTACCCAAACGGGTTTCACTTCCCCGTTGGTAAGCACGCAGCTTACTTTACAAAAGAAGACGGC
TTCATTTTGGTTGTAGCTGTACTCGGTCAGTCACAATTACCGCAAAACCACTTATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8986.22 Da        Isoelectric Point: 5.1131

>AT50203 WP_053047112.1 NZ_CP009982:c1341853-1341611 [Vibrio parahaemolyticus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKEDLAQGNVVNGEDFLRAL

Download         Length: 243 bp

>AT50203 NZ_CP009982:c1341853-1341611 [Vibrio parahaemolyticus]
ATGCACACATTAACAGCAAATGATGCAAAACGTAATTTTGGTGAGCTTCTTCTGAGCGCACAACGTGAGCCAGTAAAAAT
TAGCAAAAACAGCAAAGATGCCGTAGTTGTAATGTCTATTAAAGATTATGAAGAGCTAGAAGCTATGAAAGCTGATTACC
TTAAACATTGCTTTGAGTCCGCGAAAGAAGACCTAGCGCAAGGCAATGTGGTTAATGGTGAAGACTTCTTGCGCGCCTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References