Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1286449..1286994 Replicon chromosome
Accession NZ_CP009982
Organism Vibrio parahaemolyticus strain FORC_008

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FORC8_RS06035 Protein ID WP_053047111.1
Coordinates 1286449..1286745 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FORC8_RS06040 Protein ID WP_053047112.1
Coordinates 1286752..1286994 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC8_RS06005 1281494..1282192 + 699 WP_053047105.1 hypothetical protein -
FORC8_RS23375 1282217..1282363 + 147 WP_082241060.1 DUF3265 domain-containing protein -
FORC8_RS06010 1282386..1282799 + 414 WP_053047106.1 hypothetical protein -
FORC8_RS06015 1282987..1284312 + 1326 WP_053047107.1 SH3 domain-containing protein -
FORC8_RS24780 1284352..1284477 + 126 WP_153884734.1 hypothetical protein -
FORC8_RS06020 1284470..1285108 + 639 WP_071936819.1 hypothetical protein -
FORC8_RS06025 1285222..1285689 + 468 WP_053047825.1 hypothetical protein -
FORC8_RS06035 1286449..1286745 - 297 WP_053047111.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC8_RS06040 1286752..1286994 - 243 WP_053047112.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC8_RS06045 1287236..1287733 + 498 WP_053047113.1 hypothetical protein -
FORC8_RS23385 1287748..1287840 + 93 WP_071936820.1 DUF3265 domain-containing protein -
FORC8_RS06050 1287870..1288316 + 447 WP_053047114.1 GNAT family N-acetyltransferase -
FORC8_RS06055 1288490..1288792 + 303 WP_053047115.1 hypothetical protein -
FORC8_RS23390 1288807..1288899 + 93 WP_072829088.1 DUF3265 domain-containing protein -
FORC8_RS06060 1288936..1289649 + 714 WP_053047116.1 hypothetical protein -
FORC8_RS23395 1289664..1289756 + 93 WP_071936822.1 DUF3265 domain-containing protein -
FORC8_RS06065 1289858..1290769 + 912 WP_053047117.1 restriction endonuclease -
FORC8_RS23400 1290784..1290876 + 93 WP_071936823.1 DUF3265 domain-containing protein -
FORC8_RS06070 1290912..1291364 + 453 WP_053047119.1 hypothetical protein -
FORC8_RS23405 1291372..1291494 + 123 WP_009705224.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1277059..1383164 106105
- inside Integron - - 1277583..1354280 76697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11275.94 Da        Isoelectric Point: 9.3813

>T50202 WP_053047111.1 NZ_CP009982:c1286745-1286449 [Vibrio parahaemolyticus]
MQKNKYKLSKLAQAHLLKIKNYTVNNFSEMQWRNYKDTLLTGFQMLADNPEVGRSCDDIYPNGFHFPVGKHAAYFTKEDG
FILVVAVLGQSQLPQNHL

Download         Length: 297 bp

>T50202 NZ_CP009982:c1286745-1286449 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATATAAACTAAGTAAATTAGCTCAGGCTCATTTATTAAAAATCAAAAACTATACCGTTAATAACTT
TTCAGAGATGCAGTGGCGCAACTACAAAGATACGTTACTGACTGGATTTCAGATGCTTGCTGACAATCCGGAAGTTGGTC
GAAGTTGCGATGACATTTACCCAAACGGGTTTCACTTCCCCGTTGGTAAGCACGCAGCTTACTTTACAAAAGAAGACGGC
TTCATTTTGGTTGTAGCTGTACTCGGTCAGTCACAATTACCGCAAAACCACTTATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8986.22 Da        Isoelectric Point: 5.1131

>AT50202 WP_053047112.1 NZ_CP009982:c1286994-1286752 [Vibrio parahaemolyticus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKEDLAQGNVVNGEDFLRAL

Download         Length: 243 bp

>AT50202 NZ_CP009982:c1286994-1286752 [Vibrio parahaemolyticus]
ATGCACACATTAACAGCAAATGATGCAAAACGTAATTTTGGTGAGCTTCTTCTGAGCGCACAACGTGAGCCAGTAAAAAT
TAGCAAAAACAGCAAAGATGCCGTAGTTGTAATGTCTATTAAAGATTATGAAGAGCTAGAAGCTATGAAAGCTGATTACC
TTAAACATTGCTTTGAGTCCGCGAAAGAAGACCTAGCGCAAGGCAATGTGGTTAATGGTGAAGACTTCTTGCGCGCCTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References