Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 181752..182398 Replicon chromosome
Accession NZ_CP009962
Organism Collimonas arenae strain Cal35

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LT85_RS00815 Protein ID WP_038484139.1
Coordinates 181988..182398 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag LT85_RS00810 Protein ID WP_038494602.1
Coordinates 181752..181988 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT85_RS00795 177166..179916 + 2751 WP_038484133.1 nitrate reductase -
LT85_RS00800 179949..181142 - 1194 WP_038484136.1 MFS transporter -
LT85_RS25120 181252..181557 - 306 WP_052134462.1 hypothetical protein -
LT85_RS00810 181752..181988 + 237 WP_038494602.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LT85_RS00815 181988..182398 + 411 WP_038484139.1 type II toxin-antitoxin system VapC family toxin Toxin
LT85_RS00820 182490..184550 + 2061 WP_038484142.1 M3 family metallopeptidase -
LT85_RS00825 184628..185575 - 948 WP_052134463.1 S1/P1 nuclease -
LT85_RS00830 185810..186499 + 690 WP_172656925.1 epoxyqueuosine reductase QueH -
LT85_RS00835 186496..186720 + 225 WP_038484148.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

SpoVT-AbrB domain

(7-57)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14918.98 Da        Isoelectric Point: 4.8890

>T50178 WP_038484139.1 NZ_CP009962:181988-182398 [Collimonas arenae]
MARYMLDTNMCIYLMKNQPREVAERFATCFVGDVVMSAITYAELEYGVAASANCARQRQNLAALIEDIPVAAFDSAAASA
YGPIREATSERKKDHLDKLIAAHALALDVVLVTNNERDFANYPGVKIENWITSGNG

Download         Length: 411 bp

>T50178 NZ_CP009962:181988-182398 [Collimonas arenae]
ATGGCGCGTTACATGCTCGACACCAATATGTGCATCTATCTGATGAAAAATCAGCCGCGCGAGGTCGCTGAGCGTTTCGC
CACTTGCTTCGTCGGCGATGTGGTGATGTCGGCAATTACCTACGCTGAACTGGAATACGGCGTCGCTGCCTCGGCCAATT
GCGCGCGCCAGCGGCAGAACCTGGCTGCGCTGATAGAAGATATTCCTGTCGCTGCATTCGATAGTGCGGCGGCCAGTGCC
TACGGTCCGATCCGCGAGGCCACCAGCGAGCGCAAGAAAGACCATCTCGACAAGTTGATCGCAGCGCATGCCCTCGCGCT
CGACGTGGTACTGGTGACCAACAACGAGCGCGATTTTGCAAACTACCCTGGCGTGAAGATAGAGAATTGGATCACATCCG
GTAATGGCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8894.06 Da        Isoelectric Point: 5.1548

>AT50178 WP_038494602.1 NZ_CP009962:181752-181988 [Collimonas arenae]
MQTTKVFKNGNSQAIRIPADLAYERTDIEFEIERIGDELRIRPVGRSLGGVLKKFAQFGPDFMAEGRGEHEQSEREIL

Download         Length: 237 bp

>AT50178 NZ_CP009962:181752-181988 [Collimonas arenae]
ATGCAAACCACCAAAGTTTTCAAGAACGGCAATTCCCAGGCGATCCGGATTCCTGCCGACCTAGCCTATGAACGCACCGA
CATTGAGTTCGAGATCGAGCGCATCGGCGATGAGTTGCGGATTCGCCCGGTCGGCCGCTCTCTGGGCGGCGTTCTCAAGA
AATTCGCGCAGTTCGGTCCGGACTTCATGGCTGAAGGCCGCGGCGAGCACGAGCAAAGCGAACGCGAGATTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References