Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 1568127..1568719 | Replicon | chromosome |
Accession | NZ_CP009885 | ||
Organism | Xylella fastidiosa strain Hib4 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | Q9PD07 |
Locus tag | XFHB_RS07840 | Protein ID | WP_010894094.1 |
Coordinates | 1568127..1568423 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | XFHB_RS07845 | Protein ID | WP_004085592.1 |
Coordinates | 1568426..1568719 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFHB_RS07810 | 1563665..1564156 | - | 492 | WP_171817079.1 | glutathione peroxidase | - |
XFHB_RS14280 | 1564609..1564770 | - | 162 | WP_010894100.1 | hypothetical protein | - |
XFHB_RS07820 | 1564989..1565864 | + | 876 | WP_023906641.1 | ABC transporter ATP-binding protein | - |
XFHB_RS07825 | 1565861..1566838 | + | 978 | WP_088578153.1 | ABC transporter permease | - |
XFHB_RS07830 | 1567080..1567526 | + | 447 | WP_031336674.1 | hypothetical protein | - |
XFHB_RS07835 | 1567716..1567935 | - | 220 | Protein_1446 | tail fiber protein | - |
XFHB_RS07840 | 1568127..1568423 | + | 297 | WP_010894094.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
XFHB_RS07845 | 1568426..1568719 | + | 294 | WP_004085592.1 | putative addiction module antidote protein | Antitoxin |
XFHB_RS07850 | 1568775..1569128 | - | 354 | WP_088578042.1 | hypothetical protein | - |
XFHB_RS07855 | 1569125..1569505 | - | 381 | Protein_1450 | hypothetical protein | - |
XFHB_RS07860 | 1570043..1571059 | + | 1017 | WP_060870179.1 | peptidase M4 family protein | - |
XFHB_RS07865 | 1571067..1571420 | + | 354 | WP_081089730.1 | hypothetical protein | - |
XFHB_RS07870 | 1571444..1571716 | + | 273 | WP_088372204.1 | helix-turn-helix domain-containing protein | - |
XFHB_RS07875 | 1571688..1572254 | + | 567 | WP_088578154.1 | SocA family protein | - |
XFHB_RS07880 | 1572254..1572481 | + | 228 | WP_023906515.1 | hypothetical protein | - |
XFHB_RS07885 | 1572482..1573645 | - | 1164 | WP_088578045.1 | phage tail protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1568127..1612354 | 44227 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11167.73 Da Isoelectric Point: 9.8173
>T50121 WP_010894094.1 NZ_CP009885:1568127-1568423 [Xylella fastidiosa]
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQQRGDTIYLLLCGGDKG
LQARDIKTALHLSEQWSE
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQQRGDTIYLLLCGGDKG
LQARDIKTALHLSEQWSE
Download Length: 297 bp
>T50121 NZ_CP009885:1568127-1568423 [Xylella fastidiosa]
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCACGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCCGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCAGCGTGGCGACACGATCTACTTGCTACTTTGCGGCGGTGACAAAGGA
TTACAAGCGCGTGACATCAAGACTGCGCTGCACCTCTCTGAACAATGGAGCGAATGA
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCACGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCCGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCAGCGTGGCGACACGATCTACTTGCTACTTTGCGGCGGTGACAAAGGA
TTACAAGCGCGTGACATCAAGACTGCGCTGCACCTCTCTGAACAATGGAGCGAATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10246.59 Da Isoelectric Point: 5.6232
>AT50121 WP_004085592.1 NZ_CP009885:1568426-1568719 [Xylella fastidiosa]
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
Download Length: 294 bp
>AT50121 NZ_CP009885:1568426-1568719 [Xylella fastidiosa]
ATGACCGAGAAACTGACGAGCTACGATCCGGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCCGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAGACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCGACGCTGCGCACGACATTAGCC
GTGATGAAGGCGCTAGGGATCGAGCTCTCTGCGAAACCGTCTGGTGTTCACTGA
ATGACCGAGAAACTGACGAGCTACGATCCGGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCCGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAGACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCGACGCTGCGCACGACATTAGCC
GTGATGAAGGCGCTAGGGATCGAGCTCTCTGCGAAACCGTCTGGTGTTCACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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