50119

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1143839..1144593 Replicon chromosome
Accession NZ_CP009885
Organism Xylella fastidiosa strain Hib4

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag XFHB_RS05560 Protein ID WP_088577922.1
Coordinates 1143839..1144324 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag XFHB_RS05565 Protein ID WP_088577921.1
Coordinates 1144321..1144593 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFHB_RS05525 1139913..1140281 + 369 WP_088577960.1 hypothetical protein -
XFHB_RS05530 1140278..1140505 + 228 WP_057683524.1 hypothetical protein -
XFHB_RS05535 1140576..1140938 - 363 WP_088577961.1 PIN domain-containing protein -
XFHB_RS05540 1140935..1141189 - 255 WP_088577927.1 plasmid stability protein stbC -
XFHB_RS05545 1141443..1141757 - 315 WP_060871452.1 hypothetical protein -
XFHB_RS05550 1141825..1142418 - 594 WP_088577926.1 hypothetical protein -
XFHB_RS05555 1143403..1143588 - 186 WP_088577923.1 hypothetical protein -
XFHB_RS05560 1143839..1144324 - 486 WP_088577922.1 GNAT family N-acetyltransferase Toxin
XFHB_RS05565 1144321..1144593 - 273 WP_088577921.1 DUF1778 domain-containing protein Antitoxin
XFHB_RS05570 1144907..1145233 - 327 WP_088577962.1 DNA-binding protein -
XFHB_RS05575 1145363..1145683 - 321 WP_004091397.1 type II toxin-antitoxin system RelE/ParE family toxin -
XFHB_RS05580 1146116..1146355 + 240 WP_088577963.1 ribbon-helix-helix domain-containing protein -
XFHB_RS05585 1146355..1146774 + 420 WP_088371503.1 putative toxin-antitoxin system toxin component, PIN family -
XFHB_RS05590 1146945..1147229 + 285 WP_031337222.1 hypothetical protein -
XFHB_RS05595 1147288..1147845 + 558 WP_088578573.1 recombinase family protein -
XFHB_RS14215 1148177..1148431 - 255 Protein_1025 hypothetical protein -
XFHB_RS05605 1148698..1149123 - 426 WP_088578574.1 antirestriction protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1147288..1147845 557


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(32-148)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17817.56 Da        Isoelectric Point: 9.7126

>T50119 WP_088577922.1 NZ_CP009885:c1144324-1143839 [Xylella fastidiosa]
VNMQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVVDANQYVLGYYALAAGSVAHQEATRAIRGNM
PDPVPVMVLGRLAVDTRAQGIRLGAALLKDTVTRVQSIAENVGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIK
F

Download         Length: 486 bp

>T50119 NZ_CP009885:c1144324-1143839 [Xylella fastidiosa]
GTGAATATGCAGATTTCGACACCTCATTCACTCACGGCAGCGCATCGACTCGATGAATTCAATTGCGGTGAGCCATCGCT
GGATGATTGGCTTAAACGACGCGCATTGACCAACCATTTAAACGGGGCCAGCCGGACCTTCGTTGTTGTCGATGCCAACC
AGTACGTGCTTGGGTACTACGCTTTGGCAGCTGGGTCTGTCGCGCATCAAGAGGCCACGCGTGCTATCCGAGGTAATATG
CCTGATCCAGTGCCGGTCATGGTGCTCGGAAGGCTGGCTGTGGATACTCGCGCTCAAGGCATCAGACTCGGTGCGGCCTT
GCTTAAAGATACGGTAACTCGTGTACAGTCCATTGCAGAGAACGTCGGCGTCAGGGCATTGGTAGTGCATGCGTTGAACG
AGCGCGCAAAGCAATTCTACGAGTACTATGGTTTTCGAGCGTCACCAATGCACCTGATGACCTTGATGCTTCCGATTAAA
TTCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10281.79 Da        Isoelectric Point: 4.7419

>AT50119 WP_088577921.1 NZ_CP009885:c1144593-1144321 [Xylella fastidiosa]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLDAPQDTNLGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT50119 NZ_CP009885:c1144593-1144321 [Xylella fastidiosa]
ATGCGCGACGCTTCCATCAACTTACGTGCCATGCCTGAGCAGCGCGACTTGATTGACCAGGCTGCTAATCTATTAGGCAA
GAATCGCTCAGACTTCATGCTAGAAGCTGCGTGCGAGCGTGCGAAAGCAATTATCCTGGATCAAGTCTTTTTTAATCTGG
ACGAAGAGAGGTTCCGGCAATTCACTGTGTTGCTTGATGCGCCACAAGACACCAATCTCGGCCTTAATCGCCTGATGGCA
ATTAAGGCTCCGTGGAGCATCAGCAATACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References