Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-StbC |
Location | 1140576..1141189 | Replicon | chromosome |
Accession | NZ_CP009885 | ||
Organism | Xylella fastidiosa strain Hib4 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | XFHB_RS05535 | Protein ID | WP_088577961.1 |
Coordinates | 1140576..1140938 (-) | Length | 121 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | XFHB_RS05540 | Protein ID | WP_088577927.1 |
Coordinates | 1140935..1141189 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFHB_RS05505 | 1135819..1137219 | + | 1401 | WP_088577956.1 | P-type conjugative transfer protein TrbL | - |
XFHB_RS05510 | 1137225..1137830 | + | 606 | WP_088577957.1 | conjugal transfer protein TrbN | - |
XFHB_RS05515 | 1137895..1139145 | + | 1251 | WP_157293247.1 | hypothetical protein | - |
XFHB_RS05525 | 1139913..1140281 | + | 369 | WP_088577960.1 | hypothetical protein | - |
XFHB_RS05530 | 1140278..1140505 | + | 228 | WP_057683524.1 | hypothetical protein | - |
XFHB_RS05535 | 1140576..1140938 | - | 363 | WP_088577961.1 | PIN domain-containing protein | Toxin |
XFHB_RS05540 | 1140935..1141189 | - | 255 | WP_088577927.1 | plasmid stability protein stbC | Antitoxin |
XFHB_RS05545 | 1141443..1141757 | - | 315 | WP_060871452.1 | hypothetical protein | - |
XFHB_RS05550 | 1141825..1142418 | - | 594 | WP_088577926.1 | hypothetical protein | - |
XFHB_RS05555 | 1143403..1143588 | - | 186 | WP_088577923.1 | hypothetical protein | - |
XFHB_RS05560 | 1143839..1144324 | - | 486 | WP_088577922.1 | GNAT family N-acetyltransferase | - |
XFHB_RS05565 | 1144321..1144593 | - | 273 | WP_088577921.1 | DUF1778 domain-containing protein | - |
XFHB_RS05570 | 1144907..1145233 | - | 327 | WP_088577962.1 | DNA-binding protein | - |
XFHB_RS05575 | 1145363..1145683 | - | 321 | WP_004091397.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 121 a.a. Molecular weight: 13058.19 Da Isoelectric Point: 5.8454
>T50118 WP_088577961.1 NZ_CP009885:c1140938-1140576 [Xylella fastidiosa]
MILLDTNVVSEPLRYTPDVRIIAWIDAQPLETLYLSAMTVAELRSGVALLPIGKRREALHEDLEKNVLPMFVGRVLPFDF
ACTNAYAELLAKVRKAGRSIQTADACSKVAAGDTTVGSTP
MILLDTNVVSEPLRYTPDVRIIAWIDAQPLETLYLSAMTVAELRSGVALLPIGKRREALHEDLEKNVLPMFVGRVLPFDF
ACTNAYAELLAKVRKAGRSIQTADACSKVAAGDTTVGSTP
Download Length: 363 bp
>T50118 NZ_CP009885:c1140938-1140576 [Xylella fastidiosa]
ATGATCCTGCTCGATACGAACGTAGTTTCTGAGCCACTACGTTATACGCCGGATGTCCGCATCATTGCATGGATCGACGC
ACAACCCCTGGAGACGCTCTACCTGTCCGCAATGACTGTAGCTGAGTTGCGCTCCGGCGTGGCGCTACTACCAATTGGTA
AACGCCGTGAAGCGTTGCATGAGGACCTGGAAAAGAACGTGTTGCCCATGTTCGTTGGACGCGTGCTGCCGTTCGACTTC
GCTTGCACGAATGCTTATGCTGAGTTACTAGCGAAGGTTCGCAAGGCGGGCAGAAGTATCCAGACTGCTGACGCTTGCTC
CAAGGTGGCGGCTGGTGACACGACTGTTGGGTCTACCCCATGA
ATGATCCTGCTCGATACGAACGTAGTTTCTGAGCCACTACGTTATACGCCGGATGTCCGCATCATTGCATGGATCGACGC
ACAACCCCTGGAGACGCTCTACCTGTCCGCAATGACTGTAGCTGAGTTGCGCTCCGGCGTGGCGCTACTACCAATTGGTA
AACGCCGTGAAGCGTTGCATGAGGACCTGGAAAAGAACGTGTTGCCCATGTTCGTTGGACGCGTGCTGCCGTTCGACTTC
GCTTGCACGAATGCTTATGCTGAGTTACTAGCGAAGGTTCGCAAGGCGGGCAGAAGTATCCAGACTGCTGACGCTTGCTC
CAAGGTGGCGGCTGGTGACACGACTGTTGGGTCTACCCCATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9313.62 Da Isoelectric Point: 7.3221
>AT50118 WP_088577927.1 NZ_CP009885:c1141189-1140935 [Xylella fastidiosa]
MANVHVRNLPDAVHRALRVRAAHNGRSTEAEIREILEVAVRPPERVKLGSLLAEIGQKVKLTDEEFAIFESVRDRTPAGA
ASFE
MANVHVRNLPDAVHRALRVRAAHNGRSTEAEIREILEVAVRPPERVKLGSLLAEIGQKVKLTDEEFAIFESVRDRTPAGA
ASFE
Download Length: 255 bp
>AT50118 NZ_CP009885:c1141189-1140935 [Xylella fastidiosa]
ATGGCAAACGTACATGTAAGAAATCTACCTGATGCCGTGCATCGCGCGCTTCGCGTGCGTGCCGCCCATAATGGCCGTAG
TACCGAGGCAGAAATCCGCGAAATCCTGGAGGTCGCTGTGCGACCGCCCGAGCGTGTCAAGTTGGGTTCGCTTCTGGCCG
AGATCGGCCAGAAGGTCAAGCTGACCGACGAAGAGTTCGCTATCTTTGAGAGCGTGCGCGATAGAACACCTGCCGGTGCA
GCGAGCTTTGAATGA
ATGGCAAACGTACATGTAAGAAATCTACCTGATGCCGTGCATCGCGCGCTTCGCGTGCGTGCCGCCCATAATGGCCGTAG
TACCGAGGCAGAAATCCGCGAAATCCTGGAGGTCGCTGTGCGACCGCCCGAGCGTGTCAAGTTGGGTTCGCTTCTGGCCG
AGATCGGCCAGAAGGTCAAGCTGACCGACGAAGAGTTCGCTATCTTTGAGAGCGTGCGCGATAGAACACCTGCCGGTGCA
GCGAGCTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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