Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1140576..1141189 Replicon chromosome
Accession NZ_CP009885
Organism Xylella fastidiosa strain Hib4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XFHB_RS05535 Protein ID WP_088577961.1
Coordinates 1140576..1140938 (-) Length 121 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XFHB_RS05540 Protein ID WP_088577927.1
Coordinates 1140935..1141189 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFHB_RS05505 1135819..1137219 + 1401 WP_088577956.1 P-type conjugative transfer protein TrbL -
XFHB_RS05510 1137225..1137830 + 606 WP_088577957.1 conjugal transfer protein TrbN -
XFHB_RS05515 1137895..1139145 + 1251 WP_157293247.1 hypothetical protein -
XFHB_RS05525 1139913..1140281 + 369 WP_088577960.1 hypothetical protein -
XFHB_RS05530 1140278..1140505 + 228 WP_057683524.1 hypothetical protein -
XFHB_RS05535 1140576..1140938 - 363 WP_088577961.1 PIN domain-containing protein Toxin
XFHB_RS05540 1140935..1141189 - 255 WP_088577927.1 plasmid stability protein stbC Antitoxin
XFHB_RS05545 1141443..1141757 - 315 WP_060871452.1 hypothetical protein -
XFHB_RS05550 1141825..1142418 - 594 WP_088577926.1 hypothetical protein -
XFHB_RS05555 1143403..1143588 - 186 WP_088577923.1 hypothetical protein -
XFHB_RS05560 1143839..1144324 - 486 WP_088577922.1 GNAT family N-acetyltransferase -
XFHB_RS05565 1144321..1144593 - 273 WP_088577921.1 DUF1778 domain-containing protein -
XFHB_RS05570 1144907..1145233 - 327 WP_088577962.1 DNA-binding protein -
XFHB_RS05575 1145363..1145683 - 321 WP_004091397.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13058.19 Da        Isoelectric Point: 5.8454

>T50118 WP_088577961.1 NZ_CP009885:c1140938-1140576 [Xylella fastidiosa]
MILLDTNVVSEPLRYTPDVRIIAWIDAQPLETLYLSAMTVAELRSGVALLPIGKRREALHEDLEKNVLPMFVGRVLPFDF
ACTNAYAELLAKVRKAGRSIQTADACSKVAAGDTTVGSTP

Download         Length: 363 bp

>T50118 NZ_CP009885:c1140938-1140576 [Xylella fastidiosa]
ATGATCCTGCTCGATACGAACGTAGTTTCTGAGCCACTACGTTATACGCCGGATGTCCGCATCATTGCATGGATCGACGC
ACAACCCCTGGAGACGCTCTACCTGTCCGCAATGACTGTAGCTGAGTTGCGCTCCGGCGTGGCGCTACTACCAATTGGTA
AACGCCGTGAAGCGTTGCATGAGGACCTGGAAAAGAACGTGTTGCCCATGTTCGTTGGACGCGTGCTGCCGTTCGACTTC
GCTTGCACGAATGCTTATGCTGAGTTACTAGCGAAGGTTCGCAAGGCGGGCAGAAGTATCCAGACTGCTGACGCTTGCTC
CAAGGTGGCGGCTGGTGACACGACTGTTGGGTCTACCCCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9313.62 Da        Isoelectric Point: 7.3221

>AT50118 WP_088577927.1 NZ_CP009885:c1141189-1140935 [Xylella fastidiosa]
MANVHVRNLPDAVHRALRVRAAHNGRSTEAEIREILEVAVRPPERVKLGSLLAEIGQKVKLTDEEFAIFESVRDRTPAGA
ASFE

Download         Length: 255 bp

>AT50118 NZ_CP009885:c1141189-1140935 [Xylella fastidiosa]
ATGGCAAACGTACATGTAAGAAATCTACCTGATGCCGTGCATCGCGCGCTTCGCGTGCGTGCCGCCCATAATGGCCGTAG
TACCGAGGCAGAAATCCGCGAAATCCTGGAGGTCGCTGTGCGACCGCCCGAGCGTGTCAAGTTGGGTTCGCTTCTGGCCG
AGATCGGCCAGAAGGTCAAGCTGACCGACGAAGAGTTCGCTATCTTTGAGAGCGTGCGCGATAGAACACCTGCCGGTGCA
GCGAGCTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References